Membraneless biomolecular condensates play important roles in both normal biological
activities and responses to environmental stimuli in living organisms. Liquid‒liquid phase …

Breathtaking advances in DNA nanotechnology have established DNA as a promising
biomaterial for the fabrication of programmable higher‐order nano/microstructures. In the …

Developing strategies to activate tumor-cell-intrinsic immune response is critical for
improving tumor immunotherapy by exploiting tumor vulnerability. KDM4A, as a histone H3 …

Chemicals or drugs can accumulate within biomolecular condensates formed through phase
separation in cells. Here, we use super-resolution imaging to search for chemicals that …

Simple non-coding tandem repeats known as satellite DNA are observed widely across
eukaryotes. These repeats occupy vast regions at the centromere and pericentromere of …

The eukaryotic nucleus displays a variety of membraneless compartments with distinct
biomolecular composition and specific cellular activities. Emerging evidence indicates that …

Genome architecture and organization play critical roles in cell life. However, it remains
largely unknown how genomic loci are dynamically coordinated to regulate gene expression …

The intricacies of the 3D hierarchical organization of the genome have been approached by
many creative modeling studies. The specific model/simulation technique combination …

Chromatin organization plays a critical role in cellular function by regulating access to
genetic information. However, understanding chromatin folding is challenging due to its …

Phase separation of DNA is involved in chromatin packing for the regulation of gene
transcription. Visualization and manipulation of DNA phase separation in living cells present …