[HTML][HTML] A comprehensive review of risk factors for venous thromboembolism: from epidemiology to pathophysiology

D Pastori, VM Cormaci, S Marucci, G Franchino… - International Journal of …, 2023 - mdpi.com
Venous thromboembolism (VTE) is the third most common cause of death worldwide. The
incidence of VTE varies according to different countries, ranging from 1–2 per 1000 person …

[HTML][HTML] Guidance for the evaluation and treatment of hereditary and acquired thrombophilia

SM Stevens, SC Woller, KA Bauer, R Kasthuri… - Journal of thrombosis …, 2016 - Springer
Thrombophilias are hereditary and/or acquired conditions that predispose patients to
thrombosis. Testing for thrombophilia is commonly performed in patients with venous …

Inherited risk factors for venous thromboembolism

I Martinelli, V De Stefano, PM Mannucci - Nature Reviews Cardiology, 2014 - nature.com
Venous thromboembolism (VTE) has important heritable components. In the past 20 years,
knowledge in this field has greatly increased with the identification of a number of gene …

Therapeutic targeting of the functionally elusive TAM receptor family

YR Miao, EB Rankin, AJ Giaccia - Nature Reviews Drug Discovery, 2024 - nature.com
The TAM receptor family of TYRO3, AXL and MERTK regulates tissue and immune
homeostasis. Aberrant TAM receptor signalling has been linked to a range of diseases …

Natural anticoagulants deficiency and the risk of venous thromboembolism: a meta-analysis of observational studies

MND Di Minno, P Ambrosino, W Ageno… - Thrombosis research, 2015 - Elsevier
Introduction Natural anticoagulants deficiency (antithrombin [AT], protein C [PC], protein S
[PS]) is a rare, but potent risk factor for venous thromboembolism (VTE). We performed a …

Genetic risk factors in venous thromboembolism

C Hotoleanu - Thrombosis and Embolism: from Research to Clinical …, 2017 - Springer
Genetic risk factors predispose to thrombophilia and play the most important etiopathogenic
role in venous thromboembolism (VTE) in people younger than 50 years old. At least one …

[HTML][HTML] A comprehensive review of risk factors and thrombophilia evaluation in venous thromboembolism

AB Dicks, E Moussallem, M Stanbro, J Walls… - Journal of Clinical …, 2024 - mdpi.com
Venous thromboembolism (VTE), which encompasses deep vein thrombosis (DVT) and
pulmonary embolism (PE), is a significant cause of morbidity and mortality worldwide. There …

Causes of venous thrombosis

FR Rosendaal - Deep Vein Thrombosis and Pulmonary …, 2009 - Wiley Online Library
The incidence of venous thrombosis is 1–3 individuals per 1000 per year, with a high rate of
complications and death. Men and women are affected about equally by venous thrombosis …

Whole-exome sequencing in evaluation of patients with venous thromboembolism

EJ Lee, DJ Dykas, AD Leavitt, RM Camire… - Blood …, 2017 - ashpublications.org
Genetics play a significant role in venous thromboembolism (VTE), yet current clinical
laboratory-based testing identifies a known heritable thrombophilia (factor V Leiden …

[HTML][HTML] Pathophysiological aspects of aging in venous thromboembolism: an update

D Akrivou, G Perlepe, P Kirgou, KI Gourgoulianis… - Medicina, 2022 - mdpi.com
The aim of this review is to highlight all the factors that associate venous thromboembolism
(VTE) with aging. Elderly people are characterized by a higher incidence of thrombosis …