Abstract 18β-Glycyrrhetinic acid (GA) is the triterpenoid aglycone component of glycyrrhizic
acid, a natural product of traditional Chinese medicine, and has been proven to possess a …

Hypoxia‐induced pulmonary arterial hypertension (HPAH) is due to hypoxia caused by
vascular endothelial cell remolding and damage. Previous studies have suggested that …

Background Tibetans are genetically adapted to high-altitude environments. Though many
studies have been conducted, the genetic basis of the adaptation remains elusive due to the …

Object: This study analyses the changes of pulmonary arterial elastin expression inhibited
by hydrogen sulfide (H2S) in rats with hypoxic pulmonary hypertension. Method: The …

Background Although numerous studies have been published evaluating the positive or
negative effects of altitude on cardiovascular disease, many of them are conflicting. Methods …

Hypoxia-induced pulmonary vascular constriction and structure remodeling are the main
causes of hypoxic pulmonary hypertension. In the present study, an adeno-associated virus …

Aim Elevated pulmonary artery pressure (ePAP) in response to high-altitude hypoxia is a
critical physiopathological factor in the hypoxic adaptation that may lead to high-altitude …

Hypoxia is a condition in which tissues of the body do not receive sufficient amounts of
oxygen supply. Numerous studies have elucidated the intricate roles of hypoxia and its …

Background Hyperuricemia is a common metabolic disorder linked to various health
conditions. Its prevalence varies among populations and genders, and high-altitude …

This study investigated the effects of hydroxycitric acid tripotassium hydrate on right
ventricular function, myocardial and pulmonary vascular remodeling in rats with pulmonary …