Neoadjuvant chemoimmunotherapy for NSCLC: a systematic review and meta-analysis

M Sorin, C Prosty, L Ghaleb, K Nie, K Katergi… - JAMA …, 2024 - jamanetwork.com
Importance To date, no meta-analyses have comprehensively assessed the association of
neoadjuvant chemoimmunotherapy with clinical outcomes in non–small cell lung cancer …

PD-1/PD-L1 Inhibitors plus chemotherapy versus chemotherapy alone for resectable non-small cell lung cancer: a systematic review and meta-analysis of randomized …

E Pasqualotto, FCA Moraes, MP Chavez, MEC Souza… - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy, particularly programmed cell death protein 1 (PD-1) and
programmed death-ligand 1 (PD-L1) inhibitors, has been responsible for changing the …

International association for the study of lung cancer study of reproducibility in assessment of pathologic response in resected lung cancers after neoadjuvant therapy

S Dacic, W Travis, M Redman, A Saqi… - Journal of Thoracic …, 2023 - Elsevier
Introduction Pathologic response has been proposed as an early clinical trial end point of
survival after neoadjuvant treatment in clinical trials of NSCLC. The International Association …

Clinical characteristics and novel strategies of immune checkpoint inhibitor rechallenge therapy for non-small cell lung cancer: a comprehensive review

H Zhang, Y Hu, T Wu, Y Chen, B Yang… - Frontiers in …, 2024 - frontiersin.org
Treatment of non-small-cell lung cancer (NSCLC) has entered the immunotherapy era,
marked by significant survival improvements due to the use of immune checkpoint inhibitors …

The impact of oncogenic driver mutations on neoadjuvant immunotherapy outcomes in patients with resectable non-small cell lung cancer

Z Shen, M Teng, L Han, D Bian, J Zhang, X Zhu… - Cancer Immunology …, 2023 - Springer
Background Neoadjuvant immunotherapy has been demonstrated to be effective and safe in
resectable non-small cell lung cancer (NSCLC) patients. However, the presence of different …

Hybrid deep multi-task learning radiomics approach for predicting EGFR mutation status of non-small cell lung cancer in CT images

J Gong, F Fu, X Ma, T Wang, X Ma, C You… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Epidermal growth factor receptor (EGFR) mutation genotyping plays a pivotal role
in targeted therapy for non-small cell lung cancer (NSCLC). We aimed to develop a …

Perioperative treatment strategies in EGFR-mutant early-stage NSCLC: current evidence and future challenges

J Remon, SPL Saw, F Cortiula, PK Singh… - Journal of Thoracic …, 2023 - Elsevier
Abstract Treatment with 3-year of adjuvant osimertinib is considered a new standard in
patients with completely resected stage I-IIIA non-small cell lung cancer (NSCLC) harboring …

A real-world study comparing perioperative chemotherapy and EGFR-tyrosine kinase inhibitors for treatment of resected stage III EGFR-mutant adenocarcinoma

CL Chen, ST Wang, WC Liao, CH Chen, CY Tu… - BMC cancer, 2023 - Springer
Background The patient population with stage III non-small-cell lung cancer (NSCLC) is
heterogeneous, with varying staging characteristics and diverse treatment options. Despite …

Feasibility and safety of EGFR-TKI neoadjuvant therapy for EGFR-mutated NSCLC: A meta-analysis

Z Yu, F Xu, J Zou - European Journal of Clinical Pharmacology, 2024 - Springer
Background The role of neoadjuvant epidermal growth factor receptor (EGFR)-tyrosine
kinase inhibitor (TKI) targeted therapy for EGFR-mutated non-small cell lung cancer …

Neoadjuvant EGFR-TKI therapy in Non-Small cell lung cancer

C Grant, M Nagasaka - Cancer Treatment Reviews, 2024 - Elsevier
Non-small cell lung cancer (NSCLC) stages I-III are predominantly treated with surgery and
combination immunotherapy and chemotherapy. A majority of these studies excluded …