As food transits the gastrointestinal tract, food structures are disrupted and nutrients are
absorbed across the gut barrier. In the past decade, great efforts have focused on the …

Purpose Laryngopharyngeal reflux disease (LPRD) is a general term for the reflux of
gastroduodenal contents into the laryngopharynx, oropharynx and even the nasopharynx …

Objective Laryngopharyngeal reflux (LPR) is a common affliction that contributes to
laryngeal inflammation, symptoms that impact quality of life, and life‐threatening illnesses …

Progress continues to be made in our understanding of pepsin-mediated damage with
implications for novel therapeutic strategies. Salivary pepsin diagnostics continue to garner …

The upper aerodigestive tract (UAT) is the first line of defense against environmental
stresses such as antigens, microbes, inhalants, foods, etc., and mucins, intracellular …

Gastroesophageal reflux disease (GERD) is one of the most commonly encountered
disorders in clinical practice nowadays, with an increasing burden on healthcare systems …

Objective More than 20% of the US population suffers from laryngopharyngeal reflux.
Although dietary/lifestyle modifications and alginates provide benefit to some, there is no …

Gastroesophageal reflux disease (GERD) significantly impacts patient quality of life and is a
major risk factor for the development of Barrett's esophagus (BE) and esophageal …

Objective Otitis media (OM) is a common inflammatory disease spectrum. Cytokine
signaling, neutrophil activity, and mucin hypersecretion during recurrent and chronic OM …

Laryngeal and hypopharyngeal carcinomas are common malignant tumors of the head and
neck, and the incidence of both is increasing. Laryngopharyngeal reflux refers to the …