Therapies aiming to decrease uric acid levels prevent renal NLRP3 inflammasome
activation and exert renoprotective effects in experimental kidney diseases. However, further …

Clinical observations and preclinical studies both suggest that Down syndrome (DS) may be
associated with significant metabolic and bioenergetic alterations. However, the relevant …

Background Exposure to airborne fine particulate matter (PM 2.5) has been associated with
a variety of adverse health outcomes including chronic obstructive pulmonary disease …

Serum uric acid (UA) level is associated with the high cumulative incidence or prevalence of
coronary artery disease (CAD), and hyperuricemia is considered as an independent risk …

Background The serum level of uric acid (UA) is a well-known prognostic factor for heart
failure (HF) patients. However, the prognostic impact of hyperuricemia and the factors that …

Background The value of fractional excretion (FE) of electrolytes to characterize and
prognosticate acute kidney injury (AKI) is poorly documented in dogs. Objectives To …

We performed a retrospective cohort study of 19,237 individuals who underwent at least
three health screenings with follow-up periods of over 5 years to find a routinely checked …

Background. Hyperuricemia has long been associated with increased cardiovascular risk,
and arterial stiffness is proposed as a mediator. The present study is aimed at examining the …

Background and Objectives: Hyperuricemia is associated with several comorbidities. The
association between uric acid (UA) and pulmonary function is still a controversial issue. This …

Pulmonary hypertension (PH) is a progressive lethal disease, which is characterized by
abnormal vascular remodeling and persistently elevated pulmonary artery pressure …