Understanding ligand-protected noble metal nanoclusters at work

MF Matus, H Häkkinen - Nature Reviews Materials, 2023 - nature.com
Ligand-protected noble metal nanoclusters, commonly termed 'monolayer-protected metal
clusters'(MPCs), comprise a common set of structures with an inorganic core stabilized by an …

Nano delivery of chemotherapeutic ICD inducers for tumor immunotherapy

J Guo, Y Zou, L Huang - Small Methods, 2023 - Wiley Online Library
Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …

Cell-based drug delivery systems and their in vivo fate

L Yang, Y Yang, Y Chen, Y Xu, J Peng - Advanced Drug Delivery Reviews, 2022 - Elsevier
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …

[HTML][HTML] Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges

T Skotland, TG Iversen, A Llorente, K Sandvig - Advanced drug delivery …, 2022 - Elsevier
There is a large interest in developing nanoparticles and extracellular vesicles for delivery of
therapeutics or imaging agents. Regulatory approval of such products requires knowledge …

High‐Load Gemcitabine Inorganic–Organic Hybrid Nanoparticles as an Image‐Guided Tumor‐Selective Drug‐Delivery System to Treat Pancreatic Cancer

M Ischyropoulou, K Sabljo, L Schneider… - Advanced …, 2023 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) has a devastating prognosis without effective
treatment options. Thus, there is an urgent need for more effective and safe therapies. Here …

Antioxidative 0-dimensional nanodrugs overcome obstacles in AKI antioxidant therapy

Y Yang, Y Nan, Q Chen, Z Xiao, Y Zhang… - Journal of Materials …, 2023 - pubs.rsc.org
Acute kidney injury (AKI) is a commonly encountered syndrome associated with various
aetiologies and pathophysiological processes leading to enormous health risks and …

A tissue-adhesive F127 hydrogel delivers antioxidative copper-selenide nanoparticles for the treatment of dry eye disease

L Ou, Z Wu, X Hu, J Huang, Z Yi, Z Gong, H Li, K Peng… - Acta biomaterialia, 2024 - Elsevier
Dry eye disease (DED) is currently the most prevalent condition seen in ophthalmology
outpatient clinics, representing a significant public health issue. The onset and progression …

[HTML][HTML] Delivery of Drugs into Cancer Cells Using Antibody–Drug Conjugates Based on Receptor-Mediated Endocytosis and the Enhanced Permeability and …

T Tashima - Antibodies, 2022 - mdpi.com
Innumerable people worldwide die of cancer every year, although pharmaceutical therapy
has actualized many benefits in human health. For background, anti-cancer drug …

Antibiotic-loaded lipid-based nanocarrier: A promising strategy to overcome bacterial infection

MAB Henostroza, GD Tavares, MN Yukuyama… - International Journal of …, 2022 - Elsevier
Abstract According to the World Health Organization (WHO) and Centers for Disease Control
and Prevention (CDC), bacterial infections are one of the greatest threats to global health …

Gene-editing technology, from macromolecule therapeutics to organ transplantation: Applications, limitations, and prospective uses

GI Harisa, TM Faris, AY Sherif, RF Alzhrani… - International Journal of …, 2023 - Elsevier
Gene editing technologies (GETs) could induce gene knockdown or gene knockout for
biomedical applications. The clinical success of gene silence by RNAi therapies pays …