[HTML][HTML] Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment

H Zhao, J Zhang, X Cheng, X Nie, B He - Journal of Ovarian Research, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by
chronic ovulation dysfunction and overabundance of androgens; it affects 6–20% of women …

[HTML][HTML] Modulation of the inflammatory response in polycystic ovary syndrome (PCOS)—searching for epigenetic factors

D Szukiewicz, S Trojanowski, A Kociszewska… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age. Despite its incidence, the syndrome is poorly understood and remains …

[HTML][HTML] Insulin metabolism in polycystic ovary syndrome: secretion, signaling, and clearance

R Herman, J Sikonja, M Jensterle, A Janez… - International Journal of …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in
women of reproductive age. Its heterogeneous clinical presentation is characterized by …

[HTML][HTML] Polycystic Ovarian Syndrome (PCOS): Does the Challenge End at Conception?

FG Mirza, MA Tahlak, RB Rjeili, K Hazari… - International Journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a prevalent condition that not only has the potential to
impede conception but also represents the most common endocrine dysfunction in fertile …

[HTML][HTML] Microbial composition across body sites in polycystic ovary syndrome: a systematic review and meta-analysis

A Sola-Leyva, I Perez-Prieto, NM Molina… - Reproductive …, 2023 - Elsevier
Polycystic ovary syndrome (PCOS) is an endocrine disorder affecting reproductive-aged
women, but the cause remains unclear. Recent evidence has linked microbial composition …

Transcriptomic screening to identify hub genes and drug signatures for PCOS based on RNA-Seq data in granulosa cells

M Zanjirband, M Baharlooie, Z Safaeinejad… - Computers in Biology …, 2023 - Elsevier
Background Polycystic ovary syndrome (PCOS) is one of the most incident reproductive
diseases, and remains the main cause of female infertility. Granulosa cells play a critical role …

[HTML][HTML] Stem cells and exosomes: as biological agents in the diagnosis and treatment of polycystic ovary syndrome (PCOS)

M Hadidi, K Karimabadi, E Ghanbari… - Frontiers in …, 2023 - frontiersin.org
A typical condition of the female reproductive system is polycystic ovary syndrome (PCOS).
Hyperinsulinemia, insulin resistance, obesity, and hyperandrogenism are just a few of the …

[HTML][HTML] Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity and treatment with metformin and GLP-1s

A Etrusco, M Mikuš, A D'Amato, F Barra, P Planinić… - Biomedicines, 2024 - mdpi.com
Background: The purpose of this narrative review is to describe the mechanisms that are
responsible for the development of infertility and PCOS, with a focus on the role of obesity …

[HTML][HTML] Why does type 2 diabetes mellitus impair weight reduction in patients with obesity? A review

HE Bays - Obesity Pillars, 2023 - Elsevier
Background A common adiposopathic complication of obesity is type 2 diabetes mellitus.
Healthful weight reduction in patients with obesity can improve glucose metabolism and …

[HTML][HTML] Mesenchymal stem cells-derived exosomes as a promising new approach for the treatment of infertility caused by polycystic ovary syndrome

M Izadi, ME Rezvani, A Aliabadi, M Karimi… - Frontiers in …, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a multifactorial metabolic and most common endocrine
disorder that its prevalence, depending on different methods of evaluating PCOS traits …