Plant phenolics and phenolic-enriched extracts as antimicrobial agents against food-contaminating microorganisms

M Takó, EB Kerekes, C Zambrano, A Kotogán, T Papp… - Antioxidants, 2020 - mdpi.com
Phenolic compounds and extracts with bioactive properties can be obtained from many
kinds of plant materials. These natural substances have gained attention in the food …

Alzheimer's disease and neuroinflammation: will new drugs in clinical trials pave the way to a multi-target therapy?

D Melchiorri, S Merlo, B Micallef, JJ Borg… - Frontiers in …, 2023 - frontiersin.org
Despite extensive research, no disease-modifying therapeutic option, able to prevent, cure
or halt the progression of Alzheimer's disease [AD], is currently available. AD, a devastating …

Solvent-solute interaction, thermodynamic behaviour, structural, chemical and anti-cancer biological properties of 3 (2H)-furanone derivatives

SC Parakkal, R Datta, S Muthu, NS Alharbi… - Journal of Molecular …, 2023 - Elsevier
In this work, the structures, reactivities, and electronic and biological properties of the 3 (2H)-
furanone derivatives, 2-hydroxy-2, 5-diphenyl-4-(phenylamino) furan-3 (2H)-one (HDPF), 2 …

Secondary metabolites of the genus Nigrospora from terrestrial and marine habitats: Chemical diversity and biological activity

T Xu, Z Song, Y Hou, S Liu, X Li, Q Yang, S Wu - Fitoterapia, 2022 - Elsevier
Secondary metabolites produced by the ascomycetes have attracted wide attention from
researchers. Their diverse chemical structures and rich biological activities are essential in …

An Approach to Functionally Embellished o-Alkynylbenzoates or Furan-3(2H)-ones from Diynones and DMAD: Controlled Divergence and Product Selectivity

MJ Sarma, KA Sudarshana, P Srihari… - The Journal of Organic …, 2023 - ACS Publications
The discovery of reaction regime controlled product diversification in a one-pot reaction
between diynones and dimethyl-1, 3-acetonedicarboxylate (DMAD) to selectively furnish …

Discovery of novel α-methylene-γ-Butyrolactone derivatives containing vanillin moieties as antiviral and antifungal agents

HW He, FY Wang, D Zhang, CY Chen… - Journal of Agricultural …, 2022 - ACS Publications
On the basis of the structure of nicotlactone A (L1), a series of novel α-methylene-γ-
butyrolactone derivatives B1–B43 were designed and synthesized by structure simplification …

C− Boron Enolates Enable Palladium Catalyzed Carboboration of Internal 1, 3‐Enynes

Z Wang, J Wu, W Lamine, B Li… - Angewandte Chemie …, 2021 - Wiley Online Library
A new family of carbon‐bound boron enolates, generated by a kinetically controlled halogen
exchange between chlorocatecholborane and silylketene acetals, is described. These C …

Gold(I)-Catalyzed Cycloisomerization–Indole Addition Cascade: Synthesis of 3(2H)-Furanone-Incorporated Unsymmetrical 3,3′- Bis(indolyl)methanes

D Bag, SD Sawant - Organic Letters, 2022 - ACS Publications
An unprecedented Au (I)-catalyzed domino intramolecular carbonyl-alkyne
cyclization/indole addition strategy has been disclosed here. This generalized strategy …

Identification of isobenzofuranone derivatives as promising antidiabetic agents: Synthesis, in vitro and in vivo inhibition of α-glucosidase and α-amylase …

S Zahra, S Zaib, I Khan - International Journal of Biological Macromolecules, 2024 - Elsevier
Diabetes mellitus, one of the major health challenges of the 21st century, is associated with
numerous biomedical complications including retinopathy, neuropathy, nephropathy …

Evaluation of Senna tora (L.) Roxb. leaves as source of bioactive molecules with antioxidant, anti-inflammatory and antibacterial potential

MM Rahman, MA Al Noman, S Khatun, R Alam… - Heliyon, 2023 - cell.com
Abstract Senna tora (L.) Roxb. is an ethno-medicinal herb used by rural and tribal people of
the Satpura region of Madhya Pradesh in India and the Phatthalung Province of Thailand for …