The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

Cutaneous leishmaniasis (CL) is caused by different species of the genus Leishmania. Pro-
and anti-inflammatory cytokines play different roles in resistance/susceptibility and the …

Toll‐like receptors (TLRs) are pattern recognition receptors that recognize pathogen‐
associated molecular patterns and signal through adaptor molecules, myeloid differentiation …

ABSTRACT Stearoyl CoA desaturase 1 (SCD1) catalyzes the rate-limiting step in the
production of MUFA that are major components of tissue lipids. Alteration in SCD1 …

Transgenic mice expressing an inducible suicide gene, which allows systemic and
reversible elimination of macrophages, were developed. A macrophage-specific c-fms …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Inflammation contributes to liver injury in acetaminophen (APAP) hepatotoxicity in mice and
is triggered by stimulation of immune cells. The purinergic receptor P2X7 is upstream of the …

Background Liver transplantation is one of the most effective therapeutic options for patients
with end-stage liver diseases, and gut microbiota is actively involved in potential infections …

TNF and IL-6 are considered to be important to the initiation or priming phase of liver
regeneration. However, the signaling pathways that lead to the production of these cytokines …

Background The levels of several cytokines and chemokines are elevated in various liver
diseases, especially in fulminant hepatic failure (FHF). Activated macrophages may have a …