[HTML][HTML] Recent research on the health benefits of blueberries and their anthocyanins

W Kalt, A Cassidy, LR Howard, R Krikorian, AJ Stull… - Advances in …, 2020 - Elsevier
Awareness of the human health benefits of blueberries is underpinned by a growing body of
positive scientific evidence from human observational and clinical research, plus …

Plants vs. cancer: a review on natural phytochemicals in preventing and treating cancers and their druggability

H Wang, T Oo Khor, L Shu, ZY Su… - Anti-Cancer Agents …, 2012 - ingentaconnect.com
Cancer remains to be one of the leading causes of death in the United States and around
the world. The advent of modern drug-targeted therapies has undeniably improved cancer …

[HTML][HTML] Free radicals, antioxidants in disease and health

LA Pham-Huy, H He, C Pham-Huy - International journal of …, 2008 - ncbi.nlm.nih.gov
Free radicals and oxidants play a dual role as both toxic and beneficial compounds, since
they can be either harmful or helpful to the body. They are produced either from normal cell …

[HTML][HTML] Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals

YJ Surh, JK Kundu, HK Na - Planta medica, 2008 - thieme-connect.com
A wide array of dietary phytochemicals have been reported to induce the expression of
enzymes involved in both cellular antioxidant defenses and elimination/inactivation of …

Quercetin and the mitochondria: a mechanistic view

MR de Oliveira, SM Nabavi, N Braidy, WN Setzer… - Biotechnology …, 2016 - Elsevier
Quercetin is an important flavonoid that is ubiquitously present in the diet in a variety of fruits
and vegetables. It has been traditionally viewed as a potent antioxidant and anti …

The Nrf2/HO‐1 Axis as targets for flavanones: Neuroprotection by pinocembrin, naringenin, and Eriodictyol

S Habtemariam - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Flavanones are a group of flavonoids that derive from their immediate chalcone precursors
through the action of chalcone isomerase enzymes. The Aromatic A and B rings, C4‐keto …

TrxR1 as a potent regulator of the Nrf2-Keap1 response system

M Cebula, EE Schmidt, ESJ Arnér - Antioxidants & redox signaling, 2015 - liebertpub.com
Significance: All cells must maintain a balance between oxidants and reductants, while
allowing for fluctuations in redox states triggered by signaling, altered metabolic flow, or …

Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs

X Tang, H Wang, L Fan, X Wu, A Xin, H Ren… - Free Radical Biology …, 2011 - Elsevier
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor
regulating the expression of a battery of cytoprotective genes. Constitutive Nrf2 activation in …

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

T Satoh, SR McKercher, SA Lipton - Free Radical Biology and Medicine, 2013 - Elsevier
Living cells maintain a balance between oxidation and reduction, and perturbations of this
redox balance are thought to contribute to various diseases. Recent attempts to regulate …

Mechanisms of flavonoid protection against myocardial ischemia–reperfusion injury

M Akhlaghi, B Bandy - Journal of molecular and cellular cardiology, 2009 - Elsevier
Flavonoids have long been acknowledged for their unique antioxidant properties, and
possess other activities that may be relevant to heart ischemia–reperfusion. They may …