Chemotherapy is one of the most common treatments for cancer that uses one or more anti-
cancer drugs as a part of the standardized chemotherapy regimen. Cytotoxic chemicals …

Cancer remains a leading cause of morbidity and mortality worldwide. Hence, the increase
in cancer cases observed in the elderly population, as well as in children and adolescents …

Breast cancer (BC) is the most often diagnosed cancer among females globally and has
become an increasing global health issue over the last decades. Despite the substantial …

Objective Breast cancer is the most common and high-incidence cancer in women. It is
mainly treated by surgery combined with chemoradiation. The main challenge in treating …

Multi-drug resistance has shown to be one of the leading threats faced currently in many
chemotherapeutic agents. Permeability glycoprotein (P-gp) is an efflux transporter in …

Background Lung cancer is the leading cause of cancer-related death worldwide. Dietary
bioactives have been used as alternative therapeutics to overcome various adverse effects …

A proposed strategy to overcome multidrug resistance (MDR) of anticancer drugs in
chemotherapy is to disable the efflux function of P-glycoprotein (P-gp). In this study, based …

Abstract P-glycoprotein (P-gp), a transmembrane glycoprotein, is mainly involved in lung
cancer multidrug resistance. Several P-gp inhibitors have been developed to enhance the …

Oxidative stress causes chronic inflammation, and mediates various diseases. The
discovery of antioxidants from natural sources is important to research. Here we identified a …

The inhibition of P-glycoprotein (P-gp) has emerged as an intriguing strategy for
circumventing multidrug resistance (MDR) in anticancer chemotherapy. In this study, we …