Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …
innovative assay protocols hold great potential for the development of robust, low-cost, and …
[HTML][HTML] Adipose tissue and insulin resistance in obese
Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …
CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
Understanding the mechanisms underlying how T cells become dysfunctional in a tumor
microenvironment (TME) will greatly benefit cancer immunotherapy. We found that …
microenvironment (TME) will greatly benefit cancer immunotherapy. We found that …
[HTML][HTML] Obesity and obesity-induced inflammatory disease contribute to atherosclerosis: a review of the pathophysiology and treatment of obesity
RJ Henning - American journal of cardiovascular disease, 2021 - ncbi.nlm.nih.gov
Two billion people worldwide older than 18 years of age, or approximately 30% of the world
population, are overweight or obese. In addition, more than 43 million children under the …
population, are overweight or obese. In addition, more than 43 million children under the …
Distinct longevity mechanisms across and within species and their association with aging
Lifespan varies within and across species, but the general principles of its control remain
unclear. Here, we conducted multi-tissue RNA-seq analyses across 41 mammalian species …
unclear. Here, we conducted multi-tissue RNA-seq analyses across 41 mammalian species …
Modulation of Cardiac Arrhythmogenesis by Epicardial Adipose Tissue: JACC State-of-the-Art Review
AC Ernault, VMF Meijborg, R Coronel - Journal of the American College of …, 2021 - jacc.org
Obesity is a significant risk factor for arrhythmic cardiovascular death. Interactions between
epicardial adipose tissue (EAT) and myocytes are thought to play a key role in the …
epicardial adipose tissue (EAT) and myocytes are thought to play a key role in the …
Saturated fats and cardiovascular health: Current evidence and controversies
KC Maki, MR Dicklin, CF Kirkpatrick - Journal of clinical lipidology, 2021 - Elsevier
A diet high in saturated fatty acids (SFA) is a suspected contributor to atherosclerotic
cardiovascular disease (ASCVD) risk, in large part because of an effect to raise the low …
cardiovascular disease (ASCVD) risk, in large part because of an effect to raise the low …
Short-chain fatty acid, acylation and cardiovascular diseases
XF Chen, X Chen, X Tang - Clinical Science, 2020 - portlandpress.com
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.
Metabolic dysfunction is a fundamental core mechanism underlying CVDs. Previous studies …
Metabolic dysfunction is a fundamental core mechanism underlying CVDs. Previous studies …
Macrophage-mediated inflammation in diabetic wound repair
SJ Wolf, WJ Melvin, K Gallagher - Seminars in cell & developmental biology, 2021 - Elsevier
Non-healing wounds in Type 2 Diabetes (T2D) patients represent the most common cause
of amputation in the US, with an associated 5-year mortality of nearly 50%. Our lab has …
of amputation in the US, with an associated 5-year mortality of nearly 50%. Our lab has …
Food polyphenols and type II diabetes mellitus: pharmacology and mechanisms
Type II diabetes mellitus and its related complications are growing public health problems.
Many natural products present in our diet, including polyphenols, can be used in treating …
Many natural products present in our diet, including polyphenols, can be used in treating …