Autophagy in BRAF-mutant cutaneous melanoma: recent advances and therapeutic perspective

E Fratta, G Giurato, R Guerrieri, F Colizzi… - Cell Death …, 2023 - nature.com
Macroautophagy, hereafter referred to as autophagy, represents a highly conserved
catabolic process that maintains cellular homeostasis. At present, the role of autophagy in …

Beyond self‑eating: Emerging autophagy‑independent functions for the autophagy molecules in cancer

G Tedesco, M Santarosa… - … Journal of Oncology, 2024 - spandidos-publications.com
Autophagy is a conserved catabolic process that controls organelle quality, removes
misfolded or abnormally aggregated proteins and is part of the defense mechanisms against …

Focusing on the role of natural products in overcoming cancer drug resistance: An autophagy-based perspective

J Yao, C Ma, K Feng, G Tan, Q Wen - Biomolecules, 2022 - mdpi.com
Autophagy is a critical cellular adaptive response in tumor formation. Nutritional deficiency
and hypoxia exacerbate autophagic flux in established malignancies, promoting tumor cell …

Curcumin targeting non-coding RNAs in colorectal cancer: therapeutic and biomarker implications

J Li, R Chai, Y Chen, S Zhao, Y Bian, X Wang - Biomolecules, 2022 - mdpi.com
Colorectal cancer is one of the most common gastrointestinal malignancies, with high
incidence rates, a low rate of early diagnosis, and complex pathogenesis. In recent years …

LncRNA PRBC induces autophagy to promote breast cancer progression through modulating PABPC1-mediated mRNA stabilization

Y Liang, B Chen, F Xu, L Long, F Ye, Y Wang, D Luo… - Oncogene, 2024 - nature.com
Breast cancer is one of the major malignant tumors among women worldwide. Long
noncoding RNAs (lncRNAs) have been documented as significant modulators in the …

Role of autophagy and its regulation by noncoding RNAs in ovarian cancer

C Feng, X Yuan - Experimental Biology and Medicine, 2023 - journals.sagepub.com
Autophagy is a self-digestion process by which misfolded proteins and damaged organelles
in eukaryotic cells are degraded to maintain cellular homeostasis. This process is involved …

Critical roles of lncRNA-mediated autophagy in urologic malignancies

L Gan, L Zheng, J Zou, P Luo, T Chen, J Zou… - Frontiers in …, 2024 - frontiersin.org
Urologic oncology is a significant public health concern on a global scale. Recent research
indicates that long chain non-coding RNAs (lncRNAs) and autophagy play crucial roles in …

The role of LncRNA-mediated autophagy in cancer progression

Z Liu, J Tang, M Yang, Z Yang, J Xia - Frontiers in Cell and …, 2024 - frontiersin.org
Long non-coding RNAs (lncRNAs) are a sort of transcripts that are more than 200
nucleotides in length. In recent years, many studies have revealed the modulatory role of …

Circ_0072088 mediates hepatic fibrosis renders epithelial to mesenchymal transition through miR-330-3p/CDK1 axis in AML12 hepatocytes

M Liu, Y Xing, Y Jin, S Liu, X Teng, D Zhi, L Zhong… - 2022 - researchsquare.com
Hepatic fibrosis was one of the causes to hepatocellular cancer (HCC), owing to limited
therapeutic options. And hepatocytes can induce liver fibrogenesis via epithelial …