Immune dysfunction in uremia 2020

G Cohen - Toxins, 2020 - mdpi.com
Cardiovascular disease and infections are major causes for the high incidence of morbidity
and mortality of patients with chronic kidney disease. Both complications are directly or …

Biomarkers and mechanisms of oxidative stress—last 20 years of research with an emphasis on kidney damage and renal transplantation

K Tejchman, K Kotfis, J Sieńko - International journal of molecular …, 2021 - mdpi.com
Oxidative stress is an imbalance between pro-and antioxidants that adversely influences the
organism in various mechanisms and on many levels. Oxidative damage occurring …

Up-date on diabetic nephropathy

MC Pelle, M Provenzano, M Busutti, CV Porcu, I Zaffina… - Life, 2022 - mdpi.com
Diabetes is one of the leading causes of kidney disease. Diabetic kidney disease (DKD) is a
major cause of end-stage kidney disease (ESKD) worldwide, and it is linked to an increase …

Short-chain fatty acids in chronic kidney disease: Focus on inflammation and oxidative stress regulation

G Magliocca, P Mone, BR Di Iorio, A Heidland… - International Journal of …, 2022 - mdpi.com
Chronic Kidney Disease (CKD) is a debilitating disease associated with several secondary
complications that increase comorbidity and mortality. In patients with CKD, there is a …

Effects of air pollution on human health–mechanistic evidence suggested by in vitro and in vivo modelling

H Chen, BG Oliver, A Pant, A Olivera, P Poronnik… - Environmental …, 2022 - Elsevier
Airborne particulate matter (PM) comprises both solid and liquid particles, including carbon,
sulphates, nitrate, and toxic heavy metals, which can induce oxidative stress and …

MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 …

Y Zhang, X Le, S Zheng, K Zhang, J He, M Liu… - Stem cell research & …, 2022 - Springer
Background Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a
common cause of end-stage renal disease (ESRD). Mesenchymal stem cells (MSCs) …

Immune system dysfunction and inflammation in hemodialysis patients: two sides of the same coin

S Campo, A Lacquaniti, D Trombetta… - Journal of Clinical …, 2022 - mdpi.com
Biocompatibility in hemodialysis (HD) has considerably improved in recent decades, but
remains an open issue to be solved, appearing essential to reduce systemic inflammation …

A substituted‐rhodamine‐based reversible fluorescent probe for in vivo quantification of glutathione

N Li, T Wang, N Wang, M Fan, X Cui - Angewandte Chemie, 2023 - Wiley Online Library
Quantifying glutathione (GSH) in cells and organisms is of great significance for
understanding the mechanism of oxidative stress in various physiological and pathological …

[HTML][HTML] Cytoprotective remedies for ameliorating nephrotoxicity induced by renal oxidative stress

R Ranasinghe, M Mathai, A Zulli - Life Sciences, 2023 - Elsevier
Aims Nephrotoxicity is the hallmark of anti-neoplastic drug metabolism that causes oxidative
stress. External chemical agents and prescription drugs release copious amounts of free …

The pathogenesis of end-stage renal disease from the standpoint of the theory of general pathological processes of inflammation

E Gusev, L Solomatina, Y Zhuravleva… - International journal of …, 2021 - mdpi.com
Chronic kidney disease can progress to end-stage chronic renal disease (ESRD), which
requires the use of replacement therapy (dialysis or kidney transplant) in life-threatening …