Causal Association between Chronic Kidney Disease and Risk of 19 Site-Specific Cancers: A Mendelian Randomization Study

L Tang, C Li, W Chen, Y Zeng, H Yang, Y Hu… - … , biomarkers & prevention, 2022 - AACR
Background: Results of previous observational studies examining the risk of cancer among
patients with chronic kidney disease (CKD) are conflicting. We here explore the causal …

Oxidative stress in non-dialysis-dependent chronic kidney disease patients

P Tomás-Simó, L D'Marco, M Romero-Parra… - International Journal of …, 2021 - mdpi.com
Background: Cardiovascular complications are the leading cause of morbidity and mortality
at any stage of chronic kidney disease (CKD). Moreover, the high rate of cardiovascular …

The mechanistic role of different mediators in the pathophysiology of nephropathy: A review

J Singh, A Jain, R Bhamra, V Rathi… - Current Drug …, 2023 - ingentaconnect.com
Nephropathy has become the most common reason for end-stage renal disease worldwide.
The progression of end-stage renal disease occurs caused by decreased glomerular …

Bisdemethoxycurcumin attenuated renal injury via activation of Keap1/Nrf2 pathway in high-fat diet-fed mice

X Ding, Y Chen, L Zhou, R Wu, T Jian, H Lyu… - International Journal of …, 2022 - mdpi.com
Bisdemethoxycurcumin (BDMC), a principal and active component of edible turmeric, was
previously found to have beneficial effects on metabolic diseases. Chronic kidney disease …

Multi-mechanistic and therapeutic exploration of nephroprotective effect of traditional ayurvedic polyherbal formulation using in silico, in vitro and in vivo approaches

Gaurav, I Sharma, MU Khan, S Zahiruddin, P Basist… - Biomedicines, 2023 - mdpi.com
Based on traditional therapeutic claims, NEERI KFT (a traditional Ayurvedic polyherbal
preparation) has been innovatively developed in recent time on the decades of experience …

Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis …

Q Chen, J He, H Liu, Q Huang, S Wang, A Yin… - Journal of Translational …, 2023 - Springer
Background Substantial studies have demonstrated that oxidative stress placenta and
endothelial injury are considered to inextricably critical events in the pathogenesis of …

Intradialytic cardiovascular exercise training alters redox status, reduces inflammation and improves physical performance in patients with chronic kidney disease

A Sovatzidis, A Chatzinikolaou, IG Fatouros… - Antioxidants, 2020 - mdpi.com
Redox status (RS) perturbations and inflammation are fundamental features of chronic
kidney disease (CKD) that are substantially exacerbated in end-stage renal disease …

Effect and pharmacological mechanism of Salvia miltiorrhiza and its characteristic extracts on diabetic nephropathy

L Cai, Y Chen, H Xue, Y Yang, Y Wang, J Xu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Diabetic nephropathy (DN) is a severe diabetic
microvascular complication with an increasing prevalence rate and lack of effective …

Applications and Mechanisms of Tripterygium Wilfordii Hook. F. and its Preparations in Kidney Diseases

X Tong, Y Qiao, Y Yang, H Liu, Z Cao, B Yang… - Frontiers in …, 2022 - frontiersin.org
Tripterygium wilfordii Hook. f.(TwHF) is a Chinese botanical drug containing a large number
of metabolites. The discovered and recognized anti-inflammatory and immune-regulating …

The role of non-coding RNAs in diabetic nephropathy-related oxidative stress

X He, G Kuang, Y Zuo, S Li, S Zhou, C Ou - Frontiers in medicine, 2021 - frontiersin.org
Diabetic nephropathy (DN) is one of the main complications of diabetes and the main cause
of diabetic end-stage renal disease, which is often fatal. DN is usually characterized by …