Abstract 1, 2, 3, 4-Tetrahydro-β-carboline (THβC) scaffold is widespread in many natural
products (NPs) and synthetic compounds which show a variety of pharmacological activities …

The discovery of antifungal agents with novel structure, broad-spectrum, low toxicity, and
high efficiency has been the focus of medicinal chemists. Over the past decades, β-carboline …

The primary goal of this work was to develop a cost-effective, non-toxic, eco-friendly, and
simple approach for the green synthesis of CoFe2O4 nanoparticles (NPs) using Aloe vera …

Malaria, even though an avoidable and treatable disease, can be fatal if ignored. Artemisinin
Combination Therapy (ACT) and RTS, S/AS01 vaccine (Mosquirix™) are the only modest …

Combining two or more nanoparticles is a promising approach. Previously we have reported
synthesis of nanoparticles Dysprosium (Dy) substituted with manganese (Mn) zinc (Zn) by …

This protocol involves the NH 4 Cl catalyzed Pictet− Spengler reactions of tryptamine and
arylaldehydes in anhydrous MeOH solvent to gives corresponding tetrahydro-β-carbolines …

Leishmaniasis is the most widespread pathogenic disease in several countries. Currently,
no effective vaccines are available, and the control of Leishmaniasis primarily relies on …

Invasive Candida infections threaten human health due to the increasing incidence of
resistance to the currently available antifungal agents. Amphotericin B (AMB) is the gold …

A series of tetrahydro-ß-carbolines substituted with an alkyl or acyl side chain was
synthesized and screened for its antifungal activity against plant pathogenic fungi (Bipolaris …

The antimalarial candidate MMV008138 (1a) is of particular interest because its target
enzyme (IspD) is absent in human. To achieve higher potency, and to probe for steric …