A review of synthetic bioactive tetrahydro-β-carbolines: A medicinal chemistry perspective
J Wang, F Gong, T Liang, Z Xie, Y Yang, C Cao… - European Journal of …, 2021 - Elsevier
Abstract 1, 2, 3, 4-Tetrahydro-β-carboline (THβC) scaffold is widespread in many natural
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
Natural and synthetic β-carboline as a privileged antifungal scaffolds
JK Dai, WJ Dan, JB Wan - European Journal of Medicinal Chemistry, 2022 - Elsevier
The discovery of antifungal agents with novel structure, broad-spectrum, low toxicity, and
high efficiency has been the focus of medicinal chemists. Over the past decades, β-carboline …
high efficiency has been the focus of medicinal chemists. Over the past decades, β-carboline …
[HTML][HTML] Bioinspired ferromagnetic CoFe2O4 nanoparticles: Potential pharmaceutical and medical applications
MA Ansari, R Govindasamy, MY Begum… - Nanotechnology …, 2023 - degruyter.com
The primary goal of this work was to develop a cost-effective, non-toxic, eco-friendly, and
simple approach for the green synthesis of CoFe2O4 nanoparticles (NPs) using Aloe vera …
simple approach for the green synthesis of CoFe2O4 nanoparticles (NPs) using Aloe vera …
Structure activity relationship in β-carboline derived anti-malarial agents
A Kamboj, B Sihag, DS Brar, A Kaur… - European Journal of …, 2021 - Elsevier
Malaria, even though an avoidable and treatable disease, can be fatal if ignored. Artemisinin
Combination Therapy (ACT) and RTS, S/AS01 vaccine (Mosquirix™) are the only modest …
Combination Therapy (ACT) and RTS, S/AS01 vaccine (Mosquirix™) are the only modest …
Anti-microbial and anti-cancer activities of Mn0.5Zn0.5DyxFe2-xO4 (x ≤ 0.1) nanoparticles
SS Al-Jameel, S Rehman, MA Almessiere… - Artificial Cells …, 2021 - Taylor & Francis
Combining two or more nanoparticles is a promising approach. Previously we have reported
synthesis of nanoparticles Dysprosium (Dy) substituted with manganese (Mn) zinc (Zn) by …
synthesis of nanoparticles Dysprosium (Dy) substituted with manganese (Mn) zinc (Zn) by …
[HTML][HTML] Mild and efficient ammonium chloride catalyzed Greener synthesis of tetrahydro-β-carboline
MV Gaikwad, SV Gaikwad, RD Kamble - Current Research in Green and …, 2022 - Elsevier
This protocol involves the NH 4 Cl catalyzed Pictet− Spengler reactions of tryptamine and
arylaldehydes in anhydrous MeOH solvent to gives corresponding tetrahydro-β-carbolines …
arylaldehydes in anhydrous MeOH solvent to gives corresponding tetrahydro-β-carbolines …
[HTML][HTML] Recent evolution on synthesis strategies and anti-leishmanial activity of β-carboline derivatives–An update
KK Banoth, KVG ChandraSekhar, N Adinarayana… - Heliyon, 2020 - cell.com
Leishmaniasis is the most widespread pathogenic disease in several countries. Currently,
no effective vaccines are available, and the control of Leishmaniasis primarily relies on …
no effective vaccines are available, and the control of Leishmaniasis primarily relies on …
[HTML][HTML] Recent developments on the anti-Candida effect of amphotericin B combined with a second drug - a mini-review
DCDE Moraes - Anais da Academia Brasileira de Ciências, 2023 - SciELO Brasil
Invasive Candida infections threaten human health due to the increasing incidence of
resistance to the currently available antifungal agents. Amphotericin B (AMB) is the gold …
resistance to the currently available antifungal agents. Amphotericin B (AMB) is the gold …
[HTML][HTML] Synthesis and investigation of tetrahydro-β-carboline derivatives as inhibitors of plant pathogenic fungi
K Buaban, W Phutdhawong, T Taechowisan… - Molecules, 2021 - mdpi.com
A series of tetrahydro-ß-carbolines substituted with an alkyl or acyl side chain was
synthesized and screened for its antifungal activity against plant pathogenic fungi (Bipolaris …
synthesized and screened for its antifungal activity against plant pathogenic fungi (Bipolaris …
Probing the B-& C-rings of the antimalarial tetrahydro-β-carboline MMV008138 for steric and conformational constraints
The antimalarial candidate MMV008138 (1a) is of particular interest because its target
enzyme (IspD) is absent in human. To achieve higher potency, and to probe for steric …
enzyme (IspD) is absent in human. To achieve higher potency, and to probe for steric …