Very low-dose (0.15 mGy) chest CT protocols using the COPDGene 2 test object and a third-generation dual-source CT scanner with corresponding third-generation …

JD Newell Jr, MK Fuld, T Allmendinger… - Investigative …, 2015 - journals.lww.com
Objectives The purpose of this study was to evaluate the impact of ultralow radiation dose
single-energy computed tomographic (CT) acquisitions with Sn prefiltration and third …

A mixed phenotype of airway wall thickening and emphysema is associated with dyspnea and hospitalization for chronic obstructive pulmonary disease

N Van Tho, E Ogawa, LTH Trang, Y Ryujin… - Annals of the …, 2015 - atsjournals.org
Rationale: Quantitative computed tomography (CT) has been used to phenotype patients
with chronic obstructive pulmonary disease (COPD). A mixed phenotype is defined as the …

Quantitative computed tomography measurements of emphysema for diagnosing asthma-chronic obstructive pulmonary disease overlap syndrome

M Xie, W Wang, S Dou, L Cui… - International journal of …, 2016 - Taylor & Francis
Background The diagnostic criteria of asthma–COPD overlap syndrome (ACOS) are
controversial. Emphysema is characteristic of COPD and usually does not exist in typical …

[HTML][HTML] Relationships between emphysema and airways metrics at high-resolution computed tomography (HRCT) and ventilatory response to exercise in mild to …

E Crisafulli, V Alfieri, M Silva, M Aiello, P Tzani… - Respiratory …, 2016 - Elsevier
Abstract Background and purpose In Chronic Obstructive Pulmonary Disease (COPD)
patients, the opportunity to carry out a thoracic high-resolution CT (HRCT) scan and to …

Role of inspiratory capacity on dyspnea evaluation in COPD with or without emphysematous lesions: a pilot study

L Cui, X Ji, M Xie, S Dou, W Wang… - International journal of …, 2017 - Taylor & Francis
Background Since forced expiratory volume in 1 second (FEV1) shows a weak correlation
with patients' symptoms in COPD, some volume parameters may better reflect the change in …

Quantitative low-dose computed tomography of the lung parenchyma and airways for the differentiation between chronic obstructive pulmonary disease and asthma …

H Chen, Q Zeng, M Zhang, R Chen, T Xia, W Wang… - Respiration, 2017 - karger.com
Background: It is difficult to differentiate between chronic obstructive pulmonary disease
(COPD) and asthma in clinics; therefore, for diagnostic purposes, imaging-based …

Novel respiratory impedance-based phenotypes reflect different pathophysiologies in chronic obstructive pulmonary disease patients

Y Matsuo, E Ogawa, R Seto-Yukimura… - … journal of chronic …, 2019 - Taylor & Francis
Purpose The forced oscillation technique (FOT) is a non-invasive method to measure
respiratory impedance, the respiratory resistance (Rrs) and reactance (Xrs). The disease …

Uncontrolled asthma phenotypes defined from parameters using quantitative CT analysis

X Zhang, T Xia, Z Lai, Q Zhang, Y Guan, N Zhong - European Radiology, 2019 - Springer
Objective Asthma is a heterogeneous disease with diverse clinical phenotypes that have
been identified via cluster analyses. However, the classification of phenotypes based on …

The COPD assessment test correlates well with the computed tomography measurements in COPD patients in China

Y Zhang, YH Tu, GH Fei - International journal of chronic …, 2015 - Taylor & Francis
Background The chronic obstructive pulmonary disease (COPD) assessment test (CAT) is a
validated simple instrument to assess health status, and it correlates well with the severity of …

Relative contributions of emphysema and airway remodelling to airflow limitation in COPD: consistent results from two cohorts

NV Tho, Y Ryujin, E Ogawa, LTH Trang, R Kanda… - …, 2015 - Wiley Online Library
Background and objective The relative contributions of emphysema and airway remodelling
to airflow limitation remain unclear in chronic obstructive pulmonary disease (COPD). We …