Advanced drug delivery system against ischemic stroke
S Zhang, Y Zhou, R Li, Z Chen, X Fan - Journal of Controlled Release, 2022 - Elsevier
Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …
Harnessing nanobiotechnology for cerebral ischemic stroke management
L Tang, C Fu, A Zhang, X Li, Y Cao, J Feng, H Liu… - Biomaterials …, 2023 - pubs.rsc.org
Cerebral ischemic stroke remains one of the most serious neurological disorders that pose
threats to human health, causing a large amount of long-term disability or even death …
threats to human health, causing a large amount of long-term disability or even death …
Tailored apoptotic vesicle delivery platform for inflammatory regulation and tissue repair to ameliorate ischemic stroke
Y You, J Xu, Y Liu, H Li, L Xie, C Ma, Y Sun, S Tong… - ACS …, 2023 - ACS Publications
Apoptotic vesicles (ApoVs) hold great promise for inflammatory regulation and tissue repair.
However, little effort has been dedicated to developing ApoV-based drug delivery platforms …
However, little effort has been dedicated to developing ApoV-based drug delivery platforms …
An Ultrasmall Cu/Cu2O Nanoparticle-Based Diselenide-Bridged Nanoplatform Mediating Reactive Oxygen Species Scavenging and Neuronal Membrane …
J Kong, R Zou, R Chu, N Hu, J Liu, Y Sun, X Ge… - ACS …, 2023 - ACS Publications
Ischemic stroke is one of the major causes of death and disability worldwide, and an
effective and timely treatment of ischemic stroke has been a challenge because of the …
effective and timely treatment of ischemic stroke has been a challenge because of the …
Biomimetic Nanoplatelets to Target Delivery Hirudin for Site‐Specific Photothermal/Photodynamic Thrombolysis and Preventing Venous Thrombus Formation
Due to the high recurrence rate and mortality of venous thrombosis, there is an urgent need
for research on antithrombotic strategies. Because of the short half‐life, poor targeting …
for research on antithrombotic strategies. Because of the short half‐life, poor targeting …
Magnetic response combined with bioactive ion therapy: A RONS-scavenging theranostic nanoplatform for thrombolysis and renal ischemia–reperfusion injury
L Xu, Y Luo, Q Du, W Zhang, L Hu, N Fang, J Wang… - ACS …, 2023 - ACS Publications
Currently, the limited efficacy of antithrombotic treatments is attributed to the inadequacy of
pure drugs and the low ability of drugs to target the thrombus site. More importantly, timely …
pure drugs and the low ability of drugs to target the thrombus site. More importantly, timely …
Surface-tethered ROS-responsive micelle backpacks for boosting mesenchymal stem cell vitality and modulating inflammation in ischemic stroke treatment
Y You, Y Liu, C Ma, J Xu, L Xie, S Tong, Y Sun… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) exhibited remarkable therapeutic potential in ischemic
stroke due to their exceptional immunomodulatory ability and paracrine effect; they have …
stroke due to their exceptional immunomodulatory ability and paracrine effect; they have …
[HTML][HTML] Thrombus-specific/responsive biomimetic nanomedicine for spatiotemporal thrombolysis and alleviation of myocardial ischemia/reperfusion injury
X Guo, T Hong, J Zang, R Shao, X Hou, K Wang… - Journal of …, 2022 - Springer
Acute myocardial infarction (AMI) is usually caused by coronary thrombosis. However, the
short half-life, lack of targetability and inevitable ischemia/reperfusion injury secondary to …
short half-life, lack of targetability and inevitable ischemia/reperfusion injury secondary to …
[HTML][HTML] Engineered inhaled nanocatalytic therapy for ischemic cerebrovascular disease by inducing autophagy of abnormal mitochondria
D Wang, B Li, S Wang, Y Hao, H Wang… - NPJ Regenerative …, 2023 - nature.com
Mitochondrial dysfunction and subsequent accumulation of reactive oxygen species (ROS)
are key contributors to the pathology of ischemic cerebrovascular disease. Therefore …
are key contributors to the pathology of ischemic cerebrovascular disease. Therefore …
Plasma‐Derived Nanoclusters for Site‐Specific Multimodality Photo/Magnetic Thrombus Theranostics
Traditional thrombolytic therapeutics for vascular blockage are affected by their limited
penetration into thrombi, associated off‐target side effects, and low bioavailability, leading to …
penetration into thrombi, associated off‐target side effects, and low bioavailability, leading to …