[HTML][HTML] Evasion of host immune defenses by human papillomavirus

JA Westrich, CJ Warren, D Pyeon - Virus research, 2017 - Elsevier
A majority of human papillomavirus (HPV) infections are asymptomatic and self-resolving in
the absence of medical interventions. Various innate and adaptive immune responses, as …

Immune evasion in human papillomavirus-associated cervical cancer

RW Tindle - Nature Reviews Cancer, 2002 - nature.com
Tumour-associated viruses produce antigens that, on the face of it, are ideal targets for
immunotherapy. Unfortunately, these viruses are experts at avoiding or subverting the host …

Mechanisms used by human papillomaviruses to escape the host immune response

S Kanodia, LM Fahey, WM Kast - Current cancer drug targets, 2007 - ingentaconnect.com
The greatest risk factor for the development of cervical and other cancers that have been
linked to the human papillomavirus (HPV) family is the persistence of the virus. To persist for …

Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-γ production in human peripheral blood mononuclear and NK cells

SJ Lee, YS Cho, MC Cho, JH Shim, K Lee… - The journal of …, 2001 - journals.aai.org
Cervical carcinoma is the predominant cancer among malignancies in women throughout
the world, and human papillomavirus (HPV) 16 is the most common agent linked to human …

[PDF][PDF] HPV innate immunity

CD Woodworth - Front Biosci, 2002 - article.imrpress.com
[Frontiers in Bioscience 7, d2058-2071, October 1, 2002] 2058 HPV INNATE IMMUNITY Craig
D. Woodworth Biology Department, Clarkso Page 1 [Frontiers in Bioscience 7, d2058-2071 …

Evasion of host immunity directed by papillomavirus-encoded proteins

PM O'Brien, MS Campo - Virus research, 2002 - Elsevier
The nature of the interaction between papillomaviruses (PV) and their infected host has led
to the identification of ways in which the viral oncoproteins can transform the infected host …

[HTML][HTML] Stress keratin 17 enhances papillomavirus infection-induced disease by downregulating T cell recruitment

W Wang, A Uberoi, M Spurgeon, E Gronski… - PLoS …, 2020 - journals.plos.org
High-risk human papillomaviruses (HPVs) cause 5% of human cancers. Despite the
availability of HPV vaccines, there remains a strong urgency to find ways to treat persistent …

HPV-induced oropharyngeal cancer, immune response and response to therapy

HL Vu, AG Sikora, S Fu, J Kao - Cancer letters, 2010 - Elsevier
Approximately 25% of head and neck squamous cell carcinoma (HNSCC) worldwide are
associated with high-risk human papillomaviruses (HPV). HPV-positive HNSCCs have a …

Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment

CD Woodworth, E Michael, D Marker, S Allen… - Molecular cancer …, 2005 - AACR
The epidermal growth factor receptor (EGFR) is overexpressed in several types of human
cancer, and inhibition of EGFR function is a promising strategy for cancer therapy. We used …

Elevated systemic levels of inflammatory cytokines in older women with persistent cervical human papillomavirus infection

TJ Kemp, A Hildesheim, A García-Piñeres… - … , biomarkers & prevention, 2010 - AACR
Background: Defects in lymphoproliferative responses to mitogens/antigens in women> 45
years old with a persistent type-specific human papillomavirus (HPV) infection have been …