[HTML][HTML] Organ-on-a-chip meets artificial intelligence in drug evaluation

S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Microfluidic trends in drug screening and drug delivery

J Feng, J Neuzil, A Manz, C Iliescu, P Neuzil - TrAC Trends in Analytical …, 2023 - Elsevier
The low probability of a drug candidate's clinical success, the time consumed and the high
cost of bringing a drug from concept to market emphasizes the need for new approaches to …

Fluorescence-Enhanced Microfluidic Biosensor Platform Based on Magnetic Beads with Highly Stable ZnO Nanorods for Biomarker Detection

M Meeseepong, G Ghosh, S Shrivastava… - ACS Applied Materials …, 2023 - ACS Publications
Existing affinity-based fluorescence biosensing systems for monitoring of biomarkers often
utilize a fixed solid substrate immobilized with capture probes limiting their use in continuous …

Recent advances of biosensors on microneedles

X Ma, Q Zhou, B Gao - Analytical Methods, 2023 - pubs.rsc.org
Biosensors have attracted a considerable attention in recent years due to their enormous
potential to provide insights into the physical condition of individuals. However, the …

Recent progress of organ-on-a-chip towards cardiovascular diseases: advanced design, fabrication, and applications

H Wu, S Shi, Y Liu, Q Zhang, RHW Lam, CT Lim… - Biofabrication, 2023 - iopscience.iop.org
Cardiovascular diseases (CVDs) are a major cause of death worldwide, leading to
increased medical care costs. To turn the scale, it is essential to acquire a more in-depth and …

Progress in biomaterials for cardiac tissue engineering and regeneration

A Scafa Udriște, AG Niculescu, L Iliuță, T Bajeu… - Polymers, 2023 - mdpi.com
Cardiovascular diseases are one of the leading global causes of morbidity and mortality,
posing considerable health and economic burden on patients and medical systems …

Progress in developing microphysiological systems for biological product assessment

M Mansouri, J Lam, KE Sung - Lab on a Chip, 2024 - pubs.rsc.org
Microphysiological systems (MPS), also known as miniaturized physiological environments,
have been engineered to create and study functional tissue units capable of replicating …

Building blocks of microphysiological system to model physiology and pathophysiology of human heart

H Vuorenpää, M Björninen, H Välimäki, A Ahola… - Frontiers in …, 2023 - frontiersin.org
Microphysiological systems (MPS) are drawing increasing interest from academia and from
biomedical industry due to their improved capability to capture human physiology. MPS offer …

Application of advanced technologies—nanotechnology, genomics technology, and 3D printing technology—in precision anesthesia: a comprehensive narrative …

S Gu, Q Luo, C Wen, Y Zhang, L Liu, L Liu, S Liu… - Pharmaceutics, 2023 - mdpi.com
There has been increasing interest and rapid developments in precision medicine, which is
a new medical concept and model based on individualized medicine with the joint …

Microphysiological systems for human aging research

S Park, TC Laskow, J Chen, P Guha, B Dawn… - Aging …, 2024 - Wiley Online Library
Recent advances in microphysiological systems (MPS), also known as organs‐on‐a‐chip
(OoC), enable the recapitulation of more complex organ and tissue functions on a smaller …