RNA modification of m6A/m5C/m1A contributes to the occurrence and development of
cancer. Consequently, this study aimed to investigate the functions of m6A/m5C/m1A …

Abstract Background Immune checkpoints inhibitors (ICIs) have emerged as a treatment
option for several malignancies. Nivolumab, pembrolizumab, nivolumab plus ipilimumab …

Simple Summary Liver functional failure is one of the leading causes of cancer-related
death. Systemic chemotherapy usually offers a modest benefit in terms of disease control …

Objective T cell receptor-associated transmembrane adaptor 1 (TRAT1) is one of the hub
genes regulating T cell receptors (TCRs). Herein, the roles of TRAT1 in the prognosis and …

Background and aims The impacts of macrovascular invasion (MVI) or extrahepatic spread
(EHS) on the efficacy and safety of immune checkpoint inhibitors (ICIs) among …

Background SH2 domain containing 1A (SH2D1A) expression has been linked to cancer
progression. However, the functions of SH2D1A in hepatocellular carcinoma (HCC) have …

Background Nivolumab and pembrolizumab have not been directly compared in clinical
trials, and the aim of this study is to investigate the efficacy and safety of nivolumab versus …

Simple Summary In first clinical trials, vaccinations against tumor-associated antigens (TAA),
such as Alpha-Fetoprotein (AFP) using antigen presenting cells, such as dendritic cells …

Background. PANoptosis has been a research hotspot, but the role of PANoptosis in
hepatocellular carcinoma (HCC) remains widely unknown. Drug resistance and low …

Objective: The purpose of this study was to develop and validate a novel immune checkpoint–
related gene signature for prediction of overall survival (OS) in hepatocellular carcinoma …