The curious case of the tumour virus: 50 years of Burkitt's lymphoma
DA Thorley-Lawson, MJ Allday - Nature Reviews Microbiology, 2008 - nature.com
Burkitt's lymphoma (BL) was first described 50 years ago, and the first human tumour virus
Epstein–Barr virus (EBV) was discovered in BL tumours soon after. Since then, the role of …
Epstein–Barr virus (EBV) was discovered in BL tumours soon after. Since then, the role of …
AIDS‐related EBV‐associated smooth muscle tumors: a review of 64 published cases
B Purgina, UNM Rao, M Miettinen… - Pathology research …, 2011 - Wiley Online Library
The number of reported cases of smooth muscle tumor (SMT) arising in patients with AIDS
has been increasing since the mid‐1990s. The aim of this study is to characterize the …
has been increasing since the mid‐1990s. The aim of this study is to characterize the …
Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq
Elucidation of tumor-DNA virus associations in many cancer types has enhanced our
knowledge of fundamental oncogenesis mechanisms and provided a basis for cancer …
knowledge of fundamental oncogenesis mechanisms and provided a basis for cancer …
Host inflammatory response predicts survival of patients with Epstein-Barr virus–associated gastric carcinoma
BACKGROUND & AIMS: Lymphoepithelioma-like carcinoma (LELC) is a rare subtype of
gastric carcinoma (GC) with a better survival rate than other GCs; most cases of LELC are …
gastric carcinoma (GC) with a better survival rate than other GCs; most cases of LELC are …
Genome‐wide identification of Epstein‐Barr virus–driven promoter methylation profiles of human genes in gastric cancer cells
BACKGROUND: Aberrant methylation of tumor‐related genes has been reported in Epstein‐
Barr virus (EBV)‐associated gastric cancers. This study sought to profile EBV‐driven …
Barr virus (EBV)‐associated gastric cancers. This study sought to profile EBV‐driven …
Inflammation, ageing and cancer
Cancer is generally recognized as an age-related disease. In fact, incidence and mortality
rates of most human cancers increase consistently with age up to 90 years, but they plateau …
rates of most human cancers increase consistently with age up to 90 years, but they plateau …
Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in head and neck cancers
R Uppaluri, GP Dunn, JS Lewis Jr - Cancer immunity, 2008 - AACR
The expanding and established literature that correlates tumor infiltrating lymphocytes (TILs)
with outcomes of patients with solid tumors has contributed greatly to the appreciation of the …
with outcomes of patients with solid tumors has contributed greatly to the appreciation of the …
Viral hit and run-oncogenesis: genetic and epigenetic scenarios
HH Niller, H Wolf, J Minarovits - Cancer letters, 2011 - Elsevier
It is well documented that viral genomes either inserted into the cellular DNA or coreplicating
with it in episomal form can be lost from neoplastic cells. Therefore,“hit and run” …
with it in episomal form can be lost from neoplastic cells. Therefore,“hit and run” …
Differential B‐lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1
JP Graham, KM Arcipowski… - Immunological reviews, 2010 - Wiley Online Library
CD40 plays a vital role in humoral immunity, via its potent and multifaceted function as an
activating receptor of various immune cells, most notably B lymphocytes. The Epstein‐Barr …
activating receptor of various immune cells, most notably B lymphocytes. The Epstein‐Barr …
DNA Oncogenic Virus‐Induced Oxidative Stress, Genomic Damage, and Aberrant Epigenetic Alterations
Approximately 20% of human cancers is attributable to DNA oncogenic viruses such as
human papillomavirus (HPV), hepatitis B virus (HBV), and Epstein‐Barr virus (EBV) …
human papillomavirus (HPV), hepatitis B virus (HBV), and Epstein‐Barr virus (EBV) …