Stable isotope labelling methods in mass spectrometry-based quantitative proteomics
O Chahrour, D Cobice, J Malone - Journal of pharmaceutical and …, 2015 - Elsevier
Mass-spectrometry based proteomics has evolved as a promising technology over the last
decade and is undergoing a dramatic development in a number of different areas, such as; …
decade and is undergoing a dramatic development in a number of different areas, such as; …
Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
Protein-protein interactions (PPIs) trigger a wide range of biological signaling pathways that
are crucial for biomedical research and drug discovery. Various techniques have been used …
are crucial for biomedical research and drug discovery. Various techniques have been used …
Omics of blood pressure and hypertension
DK Arnett, SA Claas - Circulation Research, 2018 - Am Heart Assoc
Essential hypertension is a common, complex disorder affecting≤ 1 billion adults globally.
Blood pressure is a highly heritable trait, with≤ 50% of the variation between individuals …
Blood pressure is a highly heritable trait, with≤ 50% of the variation between individuals …
Label-free proteome quantification and evaluation
The label-free quantification (LFQ) has emerged as an exceptional technique in proteomics
owing to its broad proteome coverage, great dynamic ranges and enhanced analytical …
owing to its broad proteome coverage, great dynamic ranges and enhanced analytical …
[HTML][HTML] Omics technologies to understand drug toxicity mechanisms
N Nguyen, D Jennen, J Kleinjans - Drug Discovery Today, 2022 - Elsevier
Highlights•High throughput technologies (HTPs) provide quantitative and multi-dimensional
omics data.•Available HTPs can capture biological alterations in DNA, RNA, protein, and …
omics data.•Available HTPs can capture biological alterations in DNA, RNA, protein, and …
Exosomes as emerging biomarker tools in neurodegenerative and neuropsychiatric disorders—a proteomics perspective
Exosomes are synthesized and secreted by different cell types and contain proteins, lipids,
metabolites and RNA species that reflect the physiological status of the cell of origin. As …
metabolites and RNA species that reflect the physiological status of the cell of origin. As …
Comparative proteomics and phosphoproteomics analysis reveal the possible breed difference in yorkshire and duroc boar spermatozoa
Y Xu, Q Han, C Ma, Y Wang, P Zhang, C Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Sperm cells are of unique elongated structure and function, the development of which is
tightly regulated by the existing proteins and the posttranslational modifications (PTM) of …
tightly regulated by the existing proteins and the posttranslational modifications (PTM) of …
Toward biotechnology in space: High-throughput instruments for in situ biological research beyond Earth
F Karouia, K Peyvan, A Pohorille - Biotechnology advances, 2017 - Elsevier
Abstract Space biotechnology is a nascent field aimed at applying tools of modern biology to
advance our goals in space exploration. These advances rely on our ability to exploit in situ …
advance our goals in space exploration. These advances rely on our ability to exploit in situ …
Concepts and strategies of soybean seed proteomics using the shotgun proteomics approach
Introduction: The last decade has yielded significant developments in the field of proteomics,
especially in mass spectrometry (MS) and data analysis tools. In particular, a shift from gel …
especially in mass spectrometry (MS) and data analysis tools. In particular, a shift from gel …
Mechanistic insights into dietary (poly) phenols and vascular dysfunction-related diseases using multi-omics and integrative approaches: Machine learning as a next …
D Milenkovic, T Ruskovska - Molecular aspects of medicine, 2023 - Elsevier
Dietary (poly) phenols have been extensively studied for their vasculoprotective effects and
consequently their role in preventing or delaying onsets of cardiovascular and metabolic …
consequently their role in preventing or delaying onsets of cardiovascular and metabolic …