Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Nanotechnology as a promising approach to combat multidrug resistant bacteria: a comprehensive review and future perspectives

HF Hetta, YN Ramadan, AI Al-Harbi, E A. Ahmed… - Biomedicines, 2023 - mdpi.com
The wide spread of antibiotic resistance has been alarming in recent years and poses a
serious global hazard to public health as it leads to millions of deaths all over the world. The …

It's Not Easy Being Green: A Narrative Review on the Microbiology, Virulence and Therapeutic Prospects of Multidrug-Resistant Pseudomonas aeruginosa

P Behzadi, Z Baráth, M Gajdács - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa is the most frequent cause of infection among non-fermenting
Gram-negative bacteria, predominantly affecting immunocompromised patients, but its …

Mobilized colistin resistance (mcr) genes from 1 to 10: a comprehensive review

NH Hussein, IMS Al-Kadmy, BM Taha… - Molecular biology …, 2021 - Springer
At the present time, the polymyxin antibiotic colistin is considered a last-line treatment option
for severe human infections caused by multi-drug and carbapenem-resistant Gram-negative …

Emerging MDR-Pseudomonas aeruginosa in fish commonly harbor oprL and toxA virulence genes and blaTEM, blaCTX-M, and tetA antibiotic-resistance …

AM Algammal, M Mabrok, E Sivaramasamy… - Scientific reports, 2020 - nature.com
This study aimed to investigate the prevalence, antibiogram of Pseudomonas aeruginosa (P.
aeruginosa), and the distribution of virulence genes (opr L, exo S, phz M, and tox A) and the …

Detection of gyrA and parC Mutations and Prevalence of Plasmid-Mediated Quinolone Resistance Genes in Klebsiella pneumoniae

SM Kareem, IMS Al-Kadmy, SS Kazaal… - Infection and drug …, 2021 - Taylor & Francis
Background and Aim Recently, the extensive use of quinolones led to increased resistance
to these antimicrobial agents, with different rates according to the organism and the …

Bacteriophage as a novel therapeutic weapon for killing colistin-resistant multi-drug-resistant and extensively drug-resistant gram-negative bacteria

SM Mousavi, S Babakhani, L Moradi, S Karami… - Current …, 2021 - Springer
Colistin-resistant multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-
resistant (PDR) bacteria are highly lethal and many researchers have tried hard to combat …

Virulence Determinants and Plasmid-Mediated Colistin Resistance mcr Genes in Gram-Negative Bacteria Isolated From Bovine Milk

YH Tartor, RMA Gharieb, NK Abd El-Aziz… - Frontiers in cellular …, 2021 - frontiersin.org
A major increase of bacterial resistance to colistin, a last-resort treatment for severe
infections, was observed globally. Using colistin in livestock rearing is believed to be the …

Landscape of multidrug-resistant gram-negative infections in Egypt: survey and literature review

A El-Kholy, HA El-Mahallawy… - Infection and drug …, 2021 - Taylor & Francis
Purpose This article is the first to review published reports on the prevalence of multidrug-
resistant (MDR) gram-negative infections in Egypt and gain insights into antimicrobial …

Polymyxin resistance in Enterobacterales: overview and epidemiology in the Americas

J Rodríguez-Santiago, P Cornejo-Juárez… - International Journal of …, 2021 - Elsevier
The worldwide spread of carbapenem-and polymyxin-resistant Enterobacterales represents
an urgent public-health threat. However, for most countries in the Americas, the available …