The known and unknown of leptin in pregnancy

S Hauguel-de Mouzon, J Lepercq… - American journal of …, 2006 - Elsevier
Leptin, which was identified originally as an adipocyte-derived protein, was regarded for
years as an exclusive regulator of satiety and energy homeostasis. A role for leptin in …

Determinants of fetal growth

DA Sacks - Current diabetes reports, 2004 - Springer
Fetal growth is the end product of a variety of genetic, maternal, fetal, and placental factors.
Maternal size is a dominant determinant of birth weight. Specific nutrients and their …

Mitochondrial DNA depletion in small‐and large‐for‐gestational‐age newborns

C Gemma, S Sookoian, J Alvarinas, SI García… - …, 2006 - Wiley Online Library
Objective: To investigate whether mitochondrial DNA (mtDNA) content may be associated
with clinical features, anthropometric variables, and laboratory findings in both extremes of …

[HTML][HTML] Mild gestational diabetes in pregnancy and the adipoinsular axis in babies born to mothers in the ACHOIS randomised controlled trial

LK Pirc, JA Owens, CA Crowther, K Willson… - BMC pediatrics, 2007 - Springer
Background Mild gestational diabetes is a common complication of pregnancy, affecting up
to 9% of pregnant women. Treatment of mild GDM is known to reduce adverse perinatal …

[HTML][HTML] Maternal serum and cord blood leptin concentrations at delivery in normal pregnancies and in pregnancies complicated by intrauterine growth restriction

M Stefaniak, E Dmoch-Gajzlerska - Obesity Facts, 2022 - karger.com
Introduction: Leptin is a polypeptide hormone, and in pregnancy, it is secreted by the
placenta and maternal and fetal adipose tissues. Normal leptin production is a factor …

[PDF][PDF] Placental leptin and its receptor genes expression in pregnancies complicated by type 1 diabetes

R Iciek, E Wender-Ozegowska, A Zawiejska… - J Physiol …, 2013 - jpp.krakow.pl
Type 1 diabetes mellitus (T1DM) is still associated with increased risk for severe maternal
and fetal complications but their pathomechanism remains unclear. We investigated into …

Second trimester maternal leptin levels are associated with body mass index and gestational weight gain but not birth weight of the infant

S Serapio, F Ahlsson, A Larsson… - Hormone Research in …, 2020 - karger.com
Introduction: Obesity is increasing among the pregnant population. Leptin has an important
role in the regulation of energy balance and hunger. The aim of this study was to investigate …

Differential placental gene expression in term pregnancies affected by fetal growth restriction and macrosomia

A Sabri, D Lai, A D'silva, S Seeho, J Kaur… - Fetal Diagnosis and …, 2014 - karger.com
Introduction: Extremes of fetal growth are associated with increased perinatal mortality and
morbidity and a higher prevalence of cardiovascular disease, obesity and diabetes in later …

Pregnancy-induced fluctuations in functional T-cell subsets in multiple sclerosis patients

RF Neuteboom, E Verbraak… - Multiple Sclerosis …, 2010 - journals.sagepub.com
Background: During pregnancy, especially during the third trimester, multiple sclerosis (MS)
disease activity is reduced. It is not known which factors mediate this disease amelioration …

The role of leptin in fetal growth: a short review from conception to delivery

S Grisaru-Granovsky, A Samueloff, D Elstein - European Journal of …, 2008 - Elsevier
Abnormally high-or low-serum maternal levels and/or levels in placental, umbilical blood,
and fetus/neonate are associated with a wide spectrum of complicated pregnancies …