Intracellular bacteria in cancer—Prospects and debates

L Schorr, M Mathies, E Elinav, J Puschhof - npj Biofilms and …, 2023 - nature.com
Recent evidence suggests that some human cancers may harbor low-biomass microbial
ecosystems, spanning bacteria, viruses, and fungi. Bacteria, the most-studied kingdom in …

Microbes mediated immunogenic cell death in cancer immunotherapy

J Huang, F Duan, C Xie, J Xu, Y Zhang… - Immunological …, 2024 - Wiley Online Library
Immunogenic cell death (ICD) is one of the 12 distinct cell death forms, which can trigger
immune system to fight against cancer cells. During ICD, a number of cellular changes occur …

Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development

X Liang, D Chen, J Wang, B Liao, J Shen… - International Journal of …, 2023 - nature.com
Candida albicans is the most abundant fungal species in oral cavity. As a smart
opportunistic pathogen, it increases the virulence by switching its forms from yeasts to …

Engineered Microorganisms for Advancing Tumor Therapy

J Jia, X Wang, X Lin, Y Zhao - Advanced Materials, 2024 - Wiley Online Library
Engineered microorganisms have attracted significant interest as a unique therapeutic
platform in tumor treatment. Compared with conventional cancer treatment strategies …

The evil companion of OSCC: Candida albicans

Z Yang, S Zhang, N Ji, J Li, Q Chen - Oral Diseases, 2024 - Wiley Online Library
Objective Microbial dysbiosis and microbiome‐induced inflammation may play a role in the
etiopathogenesis of oral squamous cell carcinoma (OSCC). Candida albicans (C. albicans) …

Candida albicans-myeloid cells-T lymphocytes axis in the tumor microenvironment of oral tumor-bearing mice

X Wang, T Xu, S Wu, L Li, X Cai, F Chen, Z Yan - Cancer Letters, 2024 - Elsevier
Candida albicans (C. albicans) is associated with the development of oral cancer. Here, we
report the altered tumor microenvironment in oral tumor-bearing mice caused by C. albicans …

Unveiling the intratumoral microbiota within cancer landscapes

S Che, Z Yan, Y Feng, H Zhao - Iscience, 2024 - cell.com
Recent advances in cancer research have unveiled a significant yet previously
underappreciated aspect of oncology: the presence and role of intratumoral microbiota …

Mechanism-guided fine-tuned microbiome potentiates anti-tumor immunity in HCC

T Liu, Y Guo, Y Liao, J Liu - Frontiers in Immunology, 2023 - frontiersin.org
Microbiome, including bacteria, fungi, and viruses, plays a crucial role in shaping distal and
proximal anti-tumor immunity. Mounting evidence showed that commensal microbiome …

Interplay between acetylation and ubiquitination of imitation switch chromatin remodeler Isw1 confers multidrug resistance in Cryptococcus neoformans

Y Meng, Y Ni, Z Li, T Jiang, T Sun, Y Li, X Gao, H Li… - Elife, 2024 - elifesciences.org
Cryptococcus neoformans poses a threat to human health, but anticryptococcal therapy is
hampered by the emergence of drug resistance, whose underlying mechanisms remain …

New insights into the role of mycobiome in diseases

W Wu, J Ding, X Zheng, H Wang… - Frontiers in Cellular and …, 2023 - frontiersin.org
Fungi, widely distributed in nature, play important roles in maintenance of ecological
biodiversity. Although constitutes for less than 0.1% of the total gut microbiome, mycobiome …