[HTML][HTML] Mechanics in the nervous system: From development to disease
Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …
This review highlights the significance of mechanical forces in nervous system development …
[HTML][HTML] Magnetic resonance elastography in a nutshell: Tomographic imaging of soft tissue viscoelasticity for detecting and staging disease with a focus on …
T Meyer, J Castelein, J Schattenfroh, AS Morr… - Progress in Nuclear …, 2024 - Elsevier
Magnetic resonance elastography (MRE) is an emerging clinical imaging modality for
characterizing the viscoelastic properties of soft biological tissues. MRE shows great …
characterizing the viscoelastic properties of soft biological tissues. MRE shows great …
Cortical matrix remodeling as a hallmark of relapsing–remitting neuroinflammation in MR elastography and quantitative MRI
RV Silva, AS Morr, H Herthum, SP Koch, S Mueller… - Acta …, 2024 - Springer
Multiple sclerosis (MS) is a chronic neuroinflammatory disease that involves both white and
gray matter. Although gray matter damage is a major contributor to disability in MS patients …
gray matter. Although gray matter damage is a major contributor to disability in MS patients …
Combining atomic force microscopy and fluorescence-based techniques to explore mechanical properties of naive and ischemia-affected brain regions in mice
T Fuhs, B Flachmeyer, M Krueger, A Blietz, W Härtig… - Scientific Reports, 2023 - nature.com
Abstract Knowledge of the brain's structure and function is essential for understanding
processes in health and disease. Histochemical and fluorescence-based techniques have …
processes in health and disease. Histochemical and fluorescence-based techniques have …
Hippocampus of the APPNL–G–F mouse model of Alzheimer's disease exhibits region-specific tissue softening concomitant with elevated astrogliosis
Widespread neurodegeneration, enlargement of cerebral ventricles, and atrophy of cortical
and hippocampal brain structures are classic hallmarks of Alzheimer's disease (AD) …
and hippocampal brain structures are classic hallmarks of Alzheimer's disease (AD) …
Photoacoustic elasto-viscography and optical coherence microscopy for multi-parametric ex vivo brain imaging
Optical coherence microscopy (OCM) has shown the importance of imaging ex vivo brain
slices at the microscopic level for a better understanding of the disease pathology and …
slices at the microscopic level for a better understanding of the disease pathology and …
[HTML][HTML] Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury
A Carnicer-Lombarte, DG Barone, F Wronowski… - Biomaterials, 2023 - Elsevier
Spinal cord injuries have devastating consequences for humans, as mammalian neurons of
the central nervous system (CNS) cannot regenerate. In the peripheral nervous system …
the central nervous system (CNS) cannot regenerate. In the peripheral nervous system …
The networking brain: how extracellular matrix, cellular networks, and vasculature shape the in vivo mechanical properties of the brain
J Bergs, AS Morr, RV Silva, C Infante‐Duarte… - Advanced …, 2024 - Wiley Online Library
Mechanically, the brain is characterized by both solid and fluid properties. The resulting
unique material behavior fosters proliferation, differentiation, and repair of cellular and …
unique material behavior fosters proliferation, differentiation, and repair of cellular and …
[HTML][HTML] Photoacoustic viscoelasticity assessment of prefrontal cortex and cerebellum in normal and prenatal valproic acid-exposed rats
Mechanical properties of brain tissues are from principal features from different points of
view; diagnosis, the performance of the brain and neurological disorders. Particularly …
view; diagnosis, the performance of the brain and neurological disorders. Particularly …
“Patchiness” in mechanical stiffness across a tumor as an early-stage marker for malignancy
Z Mirzakhel, GA Reddy, J Boman, B Manns… - BMC Ecology and …, 2024 - Springer
Mechanical phenotyping of tumors, either at an individual cell level or tumor cell population
level is gaining traction as a diagnostic tool. However, the extent of diagnostic and …
level is gaining traction as a diagnostic tool. However, the extent of diagnostic and …