[HTML][HTML] Digital droplet PCR in hematologic malignancies: a new useful molecular tool

S Galimberti, S Balducci, F Guerrini, M Del Re… - Diagnostics, 2022 - mdpi.com
Digital droplet PCR (ddPCR) is a recent version of quantitative PCR (QT-PCR), useful for
measuring gene expression, doing clonality assays and detecting hot spot mutations. In …

A practical guide to chimerism analysis: review of the literature and testing practices worldwide

AG Blouin, F Ye, J Williams, M Askar - Human immunology, 2021 - Elsevier
Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …

Monitoring of chimerism following allogeneic haematopoietic stem cell transplantation (HSCT): technical recommendations for the use of short tandem repeat (STR) …

JR Clark, SD Scott, AL Jack, H Lee… - British journal of …, 2015 - Wiley Online Library
Analysis of short tandem repeats (STR) is the predominant method for post‐transplant
monitoring of donor engraftment. It can enable early detection of disease relapse, level of …

Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

Chimerism and outcomes after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning

F Baron, BM Sandmaier - Leukemia, 2006 - nature.com
Allogeneic hematopoietic cell transplantation (HCT) following nonmyeloablative
conditioning has been extensively evaluated in patients with hematologic malignancies who …

[HTML][HTML] Fludarabine-melphalan as preparative regimen for reduced-intensity allogeneic stem cell transplantation in relapsed and refractory Hodgkin's Lymphoma: the …

P Anderlini, R Saliba, S Acholonu, SA Giralt… - …, 2008 - ncbi.nlm.nih.gov
Results Cumulative day 100 and 2-year transplant-related mortality (TRM) were 7% and
15%, respectively (day 100 TRM MRD vs. MUD 8% vs. 6%, p= ns; 2-year MRD vs. MUD …

Quantitative analysis of chimerism after allogeneic stem cell transplantation by real‐time polymerase chain reaction with single nucleotide polymorphisms, standard …

M Koldehoff, NK Steckel, M Hlinka… - American journal of …, 2006 - Wiley Online Library
We compared the results of chimerism analyses with real‐time SNP‐PCR to those obtained
by the classical STR‐PCR method in 135 hematopoietic stem cell transplantation recipients …

[HTML][HTML] Digital PCR to assess hematopoietic chimerism after allogeneic stem cell transplantation

T Stahl, MU Böhme, N Kröger, B Fehse - Experimental hematology, 2015 - Elsevier
Analysis of hematopoietic chimerism after allogeneic stem cell transplantation represents a
crucial method to evaluate donor-cell engraftment. Whereas sensitivity of classical …

[HTML][HTML] Comparison of chimerism and minimal residual disease monitoring for relapse prediction after allogeneic stem cell transplantation for adult acute …

TH Terwey, PG Hemmati, M Nagy, H Pfeifer… - Biology of Blood and …, 2014 - Elsevier
Little data are available on the relative merits of chimerism and minimal residual disease
(MRD) monitoring for relapse prediction after allogeneic hematopoietic stem cell …

[HTML][HTML] Unmanipulated haploidentical hematopoietic stem cell transplantation achieved outcomes comparable with matched unrelated donor transplantation in young …

Y Lu, RJ Sun, YL Zhao, M Xiong, XY Cao… - Biology of Blood and …, 2018 - Elsevier
Salvage haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is considered
in patients with severe aplastic anemia (SAA) if a matched unrelated donor (MUD) is …