Assessment of donor cell engraftment after hematopoietic stem cell transplantation for sickle cell disease: A review of current and future methods

J Lewis, SC Greenway, F Khan, G Singh… - American Journal of …, 2022 - Wiley Online Library
Hematopoietic stem cell transplantation (HSCT) is the only established curative treatment for
sickle cell disease (SCD), a debilitating red blood cell (RBC) disorder with significant …

Real‐time PCR quantification of haematopoietic chimerism after transplantation: a comparison between TaqMan and hybridization probes technologies

J MARTINEZ‐LOPEZ, A Crooke… - International Journal …, 2010 - Wiley Online Library
This study aimed to compare the sensitivity and accuracy of two methods of quantitative real‐
time polymerase chain reaction (qrt‐PCR), in order to determine haematopoietic chimerism …

Impact of mother donor, peripheral blood stem cells and measurable residual disease on outcomes after haploidentical hematopoietic cell transplantation with post …

V Rocha, LJ Arcuri, A Seber, V Colturato… - Bone Marrow …, 2021 - nature.com
Haploidentical hematopoietic-cell transplantation using post-transplant cyclophosphamide
(Haplo-PTCy) is a feasible procedure in children with haematologic malignancies. However …

Minimal residual disease diagnostics and chimerism in the post‐transplant period in acute myeloid leukemia

U Bacher, T Haferlach, B Fehse… - The Scientific World …, 2011 - Wiley Online Library
In acute myeloid leukemia (AML), the selection of poor‐risk patients for allogeneic
hematopoietic stem cell transplantation (HSCT) is associated with rather high post …

Donor cell leukemia: a critical review

GJ Ruiz-Argüelles, A Ruiz-Argüelles… - Leukemia & …, 2007 - Taylor & Francis
Approximately 40 cases of DCL have been reported in the literature; cases have been
reported after allografts from bone marrow, peripheral blood and cord blood. The study of …

Can novel methods replace the gold standard chimerism method after allogeneic hematopoietic stem cell transplantation?

FA Sel, FS Oğuz - Annals of Hematology, 2024 - Springer
After hematopoietic stem cell transplantation, chimerism assay is a useful approach to
monitor the success of the transplant and to select the appropriate treatment strategy, such …

[HTML][HTML] Early achievement of full donor chimerism after allogeneic hematopoietic stem cell transplantation predicts lower relapse risk in patients with acute …

CT Chen, JP Gau, JH Liu, TJ Chiou, LT Hsiao… - Journal of the Chinese …, 2018 - Elsevier
Background Acute lymphoblastic leukemia (ALL) remains one of the most difficult-to-cure
hematological malignancies. Allogeneic hematopoietic stem cell transplantation (HSCT) …

Acute GVHD is a strong predictor of full donor CD3+ T cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation

J El‐Cheikh, A Vazquez, R Crocchiolo… - American journal of …, 2012 - Wiley Online Library
The monitoring of chimerism is a standard procedure to assess engraftment and
achievement of full donor lymphoid cells after reduced intensity conditioning (RIC) stem cell …

Standardization of DNA isolation from low cell numbers for chimerism analysis by PCR of short tandem repeats

M van der Burg, H Kreyenberg, A Willasch… - Leukemia, 2011 - nature.com
Abstract Analysis of short tandem repeats (STR) by PCR analysis is routinely used in
chimerism diagnostics to monitor donor engraftment and to diagnose relapse. Some …

[HTML][HTML] Analysis of subset chimerism for MRD-detection and pre-emptive treatment in AML

JA Georgi, S Stasik, M Bornhäuser… - Frontiers in …, 2022 - frontiersin.org
Allogeneic hematopoietic stem cell transplantation (alloHCT) represents the only potentially
curative treatment in high-risk AML patients, but up to 40% of patients suffer from relapse …