The immunology of sepsis

T van der Poll, M Shankar-Hari, WJ Wiersinga - Immunity, 2021 - cell.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection. This recently implemented definition does not capture the …

Gut Bacteroides species in health and disease

H Zafar, MH Saier Jr - Gut microbes, 2021 - Taylor & Francis
The functional diversity of the mammalian intestinal microbiome far exceeds that of the host
organism, and microbial genes contribute substantially to the well-being of the host …

Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases

G Ianiro, M Punčochář, N Karcher, S Porcari… - Nature Medicine, 2022 - nature.com
Fecal microbiota transplantation (FMT) is highly effective against recurrent Clostridioides
difficile infection and is considered a promising treatment for other microbiome-related …

Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia

L Bernard-Raichon, M Venzon, J Klein… - Nature …, 2022 - nature.com
Although microbial populations in the gut microbiome are associated with COVID-19
severity, a causal impact on patient health has not been established. Here we provide …

The microbiome-shaping roles of bacteriocins

S Heilbronner, B Krismer, H Brötz-Oesterhelt… - Nature Reviews …, 2021 - nature.com
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

Key determinants of success in fecal microbiota transplantation: From microbiome to clinic

S Porcari, N Benech, M Valles-Colomer, N Segata… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) has achieved satisfactory results in preventing the
recurrence of Clostridioides difficile infection, but these positive outcomes have only been …

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

T Tanoue, S Morita, DR Plichta, AN Skelly, W Suda… - Nature, 2019 - nature.com
There is a growing appreciation for the importance of the gut microbiota as a therapeutic
target in various diseases. However, there are only a handful of known commensal strains …

Probiotics, their prophylactic and therapeutic applications in human health development: A review of the literature

BA Tegegne, B Kebede - Heliyon, 2022 - cell.com
Antibiotics do not differentiate between good and bad germs, disrupting normal microflora
and causing vitamin deficiency in the human body. They also kill healthy bacteria in the gut …

[HTML][HTML] The spread of antibiotic resistance to humans and potential protection strategies

D Ding, B Wang, X Zhang, J Zhang, H Zhang… - Ecotoxicology and …, 2023 - Elsevier
Antibiotic resistance is currently one of the greatest threats to human health. Widespread
use and residues of antibiotics in humans, animals, and the environment can exert selective …

Current sampling methods for gut microbiota: a call for more precise devices

Q Tang, G Jin, G Wang, T Liu, X Liu… - Frontiers in cellular and …, 2020 - frontiersin.org
The development of next-generation sequencing technology has enabled researchers to
explore and understand the gut microbiome from a broader and deeper perspective …