[HTML][HTML] Epidemiology, staging, and management of multiple myeloma

SA Padala, A Barsouk, A Barsouk, P Rawla, A Vakiti… - Medical …, 2021 - mdpi.com
Multiple myeloma (MM) is a plasma cell disorder that is on the rise throughout the world,
especially in the US, Australia, and Western Europe. In the US, MM accounts for almost 2 …

Pathogenesis and treatment of multiple myeloma

P Yang, Y Qu, M Wang, B Chu, W Chen, Y Zheng… - MedComm, 2022 - Wiley Online Library
Multiple myeloma (MM) is the second‐ranking malignancy in hematological tumors. The
pathogenesis of MM is complex with high heterogeneity, and the development of the …

[HTML][HTML] Cardiovascular toxicity of carfilzomib: the real-world evidence based on the adverse event reporting system database of the FDA, the United States

Y Zhai, X Ye, F Hu, J Xu, X Guo, Y Cao, Z Lin… - Frontiers in …, 2021 - frontiersin.org
Background: Carfilzomib, an effective proteasome inhibitor agent for the therapy of relapsed
and refractory multiple myeloma, has been related to a significant number of cardiovascular …

Abnormal metaphase cytogenetics predicts venous thromboembolism in myeloma: derivation and validation of the PRISM score

R Chakraborty, L Rybicki, W Wei… - Blood, The Journal …, 2022 - ashpublications.org
Although venous thromboembolism (VTE) is an important treatment and disease-related
complication in myeloma, a validated risk prediction model including disease-specific …

Adverse event reporting in randomized clinical trials for multiple myeloma

M Najjar, J McCarron, ERS Cliff, K Berger… - JAMA Network …, 2023 - jamanetwork.com
Importance Cancer treatment can result in burdensome toxic effects that profoundly affect
patient quality of life. In seeking to emphasize the efficacy of tested treatments, clinical trial …

Recent advance of small-molecule drugs for clinical treatment of multiple myeloma

JH Zhao, QL Xu, S Ma, CY Li, HC Zhang… - European Journal of …, 2023 - Elsevier
Multiple myeloma (MM) is a hematologic neoplasm of plasma cells that is currently deemed
incurable. Despite the introduction of novel immunomodulators and proteasome inhibitors …

[HTML][HTML] Management of multiple myeloma: a review for general practitioners in oncology

BE Monteith, I Sandhu, AS Lee - Current Oncology, 2023 - mdpi.com
Multiple myeloma (MM) is a malignant clonal plasma cell disorder in the bone marrow and is
the second-most common hematologic malignancy in adults. Although patients with MM …

Patient-Reported Outcomes in Long-Term Survivors of Autologous Hematopoietic Cell Transplantation in Multiple Myeloma

R Chakraborty, J Yi, L Rybicki, J Preussler… - … and Cellular Therapy, 2023 - Elsevier
The overall survival in patients with transplantation-eligible multiple myeloma has tripled
over the past 2 decades, leading to a growing population of myeloma survivors. However …

[HTML][HTML] Enhanced Precision Therapy of Multiple Myeloma Through Engineered Biomimetic Nanoparticles with Dual Targeting

R Qi, S Wang, J Yu, T Lu, Z Bi, W Liu, Y Guo, Y Bian… - Engineering, 2024 - Elsevier
Multiple myeloma (MM) is the second most prevalent hematological malignancy. Current
MM treatment strategies are hampered by systemic toxicity and suboptimal therapeutic …

Anti‐cancer potential of selenium‐chitosan‐polyethylene glycol‐carvacrol nanocomposites in multiple myeloma U266 cells

H Zhang, J Zhao, A Chinnathambi… - … of Biochemical and …, 2023 - Wiley Online Library
Multiple myeloma (MM) is an incurable cancer that is characterized by malignant plasma cell
proliferation. Approximately 10% of all blood cancers are MM, and there is no standard …