Abstract KLF5 (Kruppel-like factor 5) is a basic transcription factor binding to GC boxes at a
number of gene promoters and regulating their transcription. KLF5 is expressed during …

In 1984, Barry Marshall and Robin Warren proposed a role for bacterial infections in the
pathogenesis of gastroduodenal disease, which triggered an avalanche of research …

Helicobacter pylori infects over half the world's population and causes a wide range of
diseases, including gastritis, peptic ulcer, and two forms of gastric cancer. H. pylori infection …

The gut microbiota has been evolving with its host along the time creating a symbiotic
relationship. In this study, we assess the role of the host genome in the modulation of the …

The well-known signal mediator and small GTPase family member, RHOA, has now been
associated with the progression of specific malignancies. In this review, we appraise the …

The most lethal aspects of gastric adenocarcinoma (GA) are its invasive and metastatic
properties. This aggressive phenotype remains poorly understood. We have recently …

Background: H. pylori infection is a major risk factor in gastric cancer development. The
availability of cDNA microarrays creates the unprecedented opportunity to examine …

Helicobacter pylori infection is associated with an inflammatory response in the gastric
mucosa, ultimately leading to cellular hyperproliferation and malignant transformation …

Here, we report unbiased screens for genes expressed in metastatic tumor cells that are
associated with cell motility. These screens identified Ier2, an immediate early gene of …

Objective: The transcriptional profile of gastric epithelial cell lines cocultured with
Helicobacter pylori and the global gene expression of whole gastric mucosa has been …