[HTML][HTML] Biological importance and therapeutic potential of Trilobatin in the management of human disorders and associated secondary complications

DK Patel - Pharmacological Research-Modern Chinese Medicine, 2022 - Elsevier
Herbal medicine, including some pure phytochemicals has been used in medicine due to
their health benefit and pharmacological activities. Lithocarpus polystachyus Rehd. has …

Endocrine, Metabolic, and Immune Pathogenesis of Postmenopausal Osteoporosis. Is there a Therapeutic Role in Natural Products?

G Lisco, D Triggiani, VA Giagulli… - … Metabolic & Immune …, 2023 - ingentaconnect.com
Background: Bone health relies on the equilibrium between resorption and new bone
generation. Postmenopausal osteoporosis depends on estrogen deficiency which favorite …

Inhibition of α-glucosidase by trilobatin and its mechanism: kinetics, interaction mechanism and molecular docking

M He, Y Zhai, Y Zhang, S Xu, S Yu, Y Wei, H Xiao… - Food & Function, 2022 - pubs.rsc.org
α-Glucosidase is related to the increase in postprandial blood glucose in vivo. Inhibition of α-
glucosidase is supposed to be an effective approach to treat type 2 diabetes mellitus …

[HTML][HTML] Flavonoid phloretin inhibits adipogenesis and increases OPG expression in adipocytes derived from human bone-marrow mesenchymal stromal-cells

A Casado-Díaz, Á Rodríguez-Ramos… - Nutrients, 2021 - mdpi.com
Phloretin (a flavonoid abundant in apple), has antioxidant, anti-inflammatory, and glucose-
transporter inhibitory properties. Thus, it has interesting pharmacological and nutraceutical …

Aloe emodin 3-O-glucoside inhibits cell growth and migration and induces apoptosis of non-small-cell lung cancer cells via suppressing MEK/ERK and Akt signalling …

HJ Kim, JW Choi, J Ree, JS Lim, J Lee, JI Kim… - Life Sciences, 2022 - Elsevier
Aims Non-small-cell lung cancer (NSCLC) is the most frequent type of lung cancer with a
high mortality rate. Glycosylation of phenolic compounds may increase water-solubility and …

Trilobatin regulates glucose metabolism by ameliorating oxidative stress and insulin resistance in vivo and in vitro

M He, Y Zhang, Y Zhai, Y Li, G Yang… - Journal of Pharmacy …, 2024 - academic.oup.com
Objectives Trilobatin, a glycosylated dihydrochalcone, has been reported to have anti-
diabetic properties. However, the underlying mechanism remains unexplained. Methods In …

Targeted Biological and Cellular Immunotherapies for Osteosarcoma

GM Robbins - 2023 - search.proquest.com
Osteosarcoma (OSA) is the most common cancer of the bone and third most common cancer
diagnosed in children and adolescent. The five-year survival rate for OSA patients …