The barrier properties of endothelial cells are critical for the maintenance of water and
protein balance between the intravascular and extravascular compartments. An impairment …

Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …

Ebola virus disease causes widespread and highly fatal epidemics in human populations.
Today, there is still great need for point-of-care tests for diagnosis, patient management and …

Four families of enveloped RNA viruses, filoviruses, flaviviruses, arenaviruses, and
bunyaviruses, cause hemorrhagic fevers. These viruses are maintained in specific natural …

The systemic capillary leak syndrome (SCLS) is a rare disease of reversible plasma
extravasation and vascular collapse accompanied by hemoconcentration and …

Ebolavirus (EBOV) is a highly virulent pathogen capable of causing a severe hemorrhagic
fever with 50–90% lethality. The EBOV glycoprotein (GP) is the only virally expressed …

The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

Virus entry into host cells is the first step of infection and a crucial determinant of
pathogenicity. Here we show that Ebola virus-like particles (EBOV-VLPs) composed of the …

There are several reasons to consider the role of endothelial cells in COVID-19 and other
emerging viral infections. First, severe cases of COVID-19 show a common breakdown of …

Background Safe and effective vaccines against Ebola could prevent or control outbreaks.
The safe use of replication-competent vaccines requires a careful dose-selection process …