In the young of many mammalian species, including humans, a vigorous and highly
rewarding social activity is abundantly expressed, known as social play behaviour. Social …

The rewarding properties of social interactions are essential for the expression of social
behavior and the development of adaptive social relationships. Here, we review sex …

Social reward is critical for social relationships, and yet we know little about the
characteristics of social interactions that are rewarding or the neural mechanisms underlying …

Individuals living with human immunodeficiency virus type 1 (HIV-1) are often plagued by
debilitating neurocognitive impairments and affective alterations; the pathophysiology …

Rats are highly social animals and social play during adolescence has an important role for
social development, hence post-weaning social isolation is widely used to study the adverse …

Opioid addiction is a chronic and relapsing mental health disorder. However, only some
individuals exposed to opioids, either recreationally or during the course of pain …

Drug addiction is a multifactorial disorder resulting from the complex interaction between
biological, environmental and drug-induced effects. Generally, stress is a well-known risk …

Adolescence is a period of incredible change, especially within the brain's reward circuitry.
Stress, including social isolation, during this time has profound effects on behaviors …

Early life adversity can disrupt development leading to emotional and cognitive disorders.
This study investigated the effects of social isolation after weaning on anxiety, body weight …

Adolescence is known for its high level of risk-taking, and neurobiological alterations during
this period may predispose to psychoactive drug initiation and progression into more severe …