The impact of pre-existing comorbidities and therapeutic interventions on COVID-19

LA Callender, M Curran, SM Bates… - Frontiers in …, 2020 - frontiersin.org
Evidence from the global outbreak of SARS-CoV-2 has clearly demonstrated that individuals
with pre-existing comorbidities are at a much greater risk of dying from COVID-19. This is of …

American College of Rheumatology guidance for the management of rheumatic disease in adult patients during the COVID‐19 pandemic: version 1

TR Mikuls, SR Johnson, L Fraenkel… - Arthritis & …, 2020 - Wiley Online Library
Objective To provide guidance to rheumatology providers on the management of adult
rheumatic disease in the context of the coronavirus disease 2019 (COVID‐19) pandemic …

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …

Naringenin, a flavanone with antiviral and anti‐inflammatory effects: A promising treatment strategy against COVID‐19

H Tutunchi, F Naeini, A Ostadrahimi… - Phytotherapy …, 2020 - Wiley Online Library
At the end of 2019, a novel flu‐like coronavirus named COVID‐19 (coronavirus disease
2019) was recognized by World Health Organization. No specific treatments exist for COVID …

Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

A Aslan, C Aslan, NM Zolbanin, R Jafari - Pneumonia, 2021 - Springer
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …

Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement

P Nash, A Kerschbaumer, T Dörner… - Annals of the …, 2021 - ard.bmj.com
Objectives Janus kinase inhibitors (JAKi) have been approved for use in various immune-
mediated inflammatory diseases. With five agents licensed, it was timely to summarise the …

Overview of SARS-CoV-2 infection in adults living with HIV

J Ambrosioni, JL Blanco, JM Reyes-Urueña… - The lancet HIV, 2021 - thelancet.com
Around 2· 5 million deaths and more than 110 million COVID-19 cases have been reported
globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or …

[HTML][HTML] SARS-CoV-2 and COVID-19: Is interleukin-6 (IL-6) the 'culprit lesion'of ARDS onset? What is there besides Tocilizumab? SGP130Fc

G Magro - Cytokine: X, 2020 - Elsevier
Since the outbreak of COVID-19 many studies have been published showing possible
therapies, here the author discusses the end of stage disease related drugs, like …

Baricitinib: a review of pharmacology, safety, and emerging clinical experience in COVID‐19

SCJ Jorgensen, CLY Tse, L Burry… - … : The Journal of …, 2020 - Wiley Online Library
A hyperinflammatory response to severe acute respiratory syndrome‐coronavirus 2 (SARS‐
CoV‐2) infection, reminiscent of cytokine release syndrome, has been implicated in the …

Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …