Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …

Introduction: Advancements in cancer management and treatment are associated with
strong preclinical research data, in which reliable cancer models are demanded. Indeed …

Background Surufatinib showed superior efficacy in extrapancreatic neuroendocrine
tumours (NETs) in the phase 3 SANET-ep study. In SANET-p, we aimed to assess the …

Summary The European Society for Medical Oncology (ESMO) suggests the use of
chemotherapy as neoadjuvant, adjuvant, and concomitant to surgery and radiotherapy for …

Neuroendocrine tumors (NETs) are rare, heterogeneous, often indolent tumors that
predominantly originate in the lungs and gastrointestinal tract. An understanding of the …

Metastatic pheochromocytomas and paragangliomas are rare, highly vascular tumors that
spread primarily to the lymph nodes, skeletal tissue, lungs, and liver. Tumor morbidity is …

The incidence of melanoma has increased rapidly over the past few decades, with mortality
accounting for more than 75% of all skin cancers. The high metastatic potential of Melanoma …

Simple Summary The medical care for patients with neuroendocrine tumors arising from the
intestines, pancreas, or stomach is frequently limited by the development resistance to …

Simple Summary Tumor resistance, both primary and acquired, is leading to increased
complexity in the nonsurgical treatment of patients with advanced panNENs, which would be …

Purpose Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) form a rare and
remarkably heterogeneous group of tumors. Therefore, establishing personalized therapies …