Health benefits and side effects of short-chain fatty acids

RG Xiong, DD Zhou, SX Wu, SY Huang, A Saimaiti… - Foods, 2022 - mdpi.com
The gut microbiota and their metabolites could play an important role in health and diseases
of human beings. Short-chain fatty acids (SCFAs) are mainly produced by gut microbiome …

Gut microbiota: a novel therapeutic target for Parkinson's disease

M Zhu, X Liu, Y Ye, X Yan, Y Cheng, L Zhao… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by motor dysfunction. Growing evidence has demonstrated that gut dysbiosis …

Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial

AC Schaub, E Schneider… - Translational …, 2022 - nature.com
A promising new treatment approach for major depressive disorder (MDD) targets the
microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions …

Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial

P Tian, Y Chen, H Zhu, L Wang, X Qian, R Zou… - Brain, behavior, and …, 2022 - Elsevier
Objective Psychobiotics, as a novel class of probiotics mainly acting on the gut-brain axis,
have shown promising prospects in treating psychiatric disorders. Bifidobacterium breve …

Probiotics (Lactobacillus plantarum HNU082) supplementation relieves ulcerative colitis by affecting intestinal barrier functions, immunity-related gene expression, gut …

Y Wu, R Jha, A Li, H Liu, Z Zhang, C Zhang… - Microbiology …, 2022 - Am Soc Microbiol
Probiotics can effectively improve ulcerative colitis (UC), but the mechanism is still unclear.
Here, shotgun metagenome and transcriptome analyses were performed to explore the …

Neuromicrobiology, an emerging neurometabolic facet of the gut microbiome?

S Miri, JD Yeo, S Abubaker, R Hammami - Frontiers in Microbiology, 2023 - frontiersin.org
The concept of the gut microbiome is emerging as a metabolic interactome influenced by
diet, xenobiotics, genetics, and other environmental factors that affect the host's absorption …

A comprehensive review of the application of probiotics and postbiotics in oral health

A Homayouni Rad, H Pourjafar… - Frontiers in cellular and …, 2023 - frontiersin.org
Oral diseases are among the most common diseases around the world that people usually
suffer from during their lifetime. Tooth decay is a multifactorial disease, and the composition …

Cross-talks between gut microbiota and tobacco smoking: a two-sample Mendelian randomization study

J Fan, Y Zhou, R Meng, J Tang, J Zhu, MC Aldrich… - BMC medicine, 2023 - Springer
Background Considerable evidence has been reported that tobacco use could cause
alterations in gut microbiota composition. The microbiota-gut–brain axis also in turn hinted at …

Coix seed polysaccharides alleviate type 2 diabetes mellitus via gut microbiota-derived short-chain fatty acids activation of IGF1/PI3K/AKT signaling

T Xia, CS Liu, YN Hu, ZY Luo, FL Chen, LX Yuan… - Food Research …, 2021 - Elsevier
Type 2 diabetes mellitus (T2DM) has become a worldwide concern in recent years. Coix
seed (CS) as a homologous substance of traditional Chinese medicine and food, its …

Akkermansia muciniphila in neuropsychiatric disorders: friend or foe?

W Lei, Y Cheng, J Gao, X Liu, L Shao… - Frontiers in cellular …, 2023 - frontiersin.org
An accumulating body of evidence suggests that the bacterium Akkermansia muciniphila
exhibits positive systemic effects on host health, mainly by improving immunological and …