The essential role of light-induced autophagy in the inner choroid/outer retinal neurovascular unit in baseline conditions and degeneration

R Pinelli, M Ferrucci, C Berti, F Biagioni… - International journal of …, 2023 - mdpi.com
The present article discusses the role of light in altering autophagy, both within the outer
retina (retinal pigment epithelium, RPE, and the outer segment of photoreceptors) and the …

Antioxidants in Photoaging: From Molecular Insights to Clinical Applications

MJ Calvo, C Navarro, P Durán… - International Journal of …, 2024 - mdpi.com
Photoaging (PA) is considered a silent disease affecting millions of people globally and is
defined as skin damage due to prolonged exposure to ultraviolet radiation (UVR) from the …

Palmatine treats urticaria by reducing inflammation and increasing autophagy

T Xiao, X Yu, L Yang, X Duan - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Chronic spontaneous urticaria (CSU) is mainly manifested as wheals and
erythema on the skin accompanied by itching, which will cause emotional anxiety and …

Skin Anti-Aging Effect of Oral Vitamin A Supplementation in Combination with Topical Retinoic Acid Treatment in Comparison with Topical Treatment Alone: A …

M Milani, F Colombo - Cosmetics, 2023 - mdpi.com
Topical retinoid treatment is considered a standard therapeutic approach for chrono and
photo skin aging. Retinol (vitamin A) is the precursor of endogenous retinoids. A …

Ultraviolet Light, Unfolded Protein Response and Autophagy

VA Bahamondes Lorca, S Wu - Photochemistry and …, 2023 - Wiley Online Library
The endoplasmic reticulum (ER) plays an important role in the regulation of protein
synthesis. Alterations in the folding capacity of the ER induce stress, which activates three …

Ultraviolet radiation biological and medical implications

T Al-Sadek, N Yusuf - Current Issues in Molecular Biology, 2024 - mdpi.com
Ultraviolet (UV) radiation plays a crucial role in the development of melanoma and non-
melanoma skin cancers. The types of UV radiation are differentiated by wavelength: UVA …

The multifaceted role of autophagy in skin autoimmune disorders: a guardian or culprit?

Y Lin, X Wu, Y Yang, Y Wu, L Xiang… - Frontiers in …, 2024 - frontiersin.org
Autophagy is a cellular process that functions to maintain intracellular homeostasis via the
degradation and recycling of defective organelles or damaged proteins. This dynamic …

Kangfuxin liquid reduces the ultraviolet B-induced photodamage of HaCaT cells by regulating autophagy

X Lin, J Chu, Y Xiang, M He, Q Ma… - Bioscience …, 2023 - academic.oup.com
Kangfuxin liquid (KFX), an extract of the American cockroach, has been clinically proven to
be effective in various skin damage disorders, but there are no reports on its use in …

[HTML][HTML] Handelin protects human skin keratinocytes against ultraviolet B-induced photodamage via autophagy activation by regulating the AMPK-mTOR signaling …

J Chu, Y Xiang, X Lin, M He, Y Wang, Q Ma… - Archives of Biochemistry …, 2023 - Elsevier
Handelin is a natural ingredient extracted from Chrysanthemum boreale flowers that has
been shown to decrease stress-related cell death, prolong lifespan, and promote anti …

[HTML][HTML] Autophagy in Its (Proper) Context: Molecular Basis, Biological Relevance, Pharmacological Modulation, and Lifestyle Medicine

MA Ortega, O Fraile-Martinez… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Autophagy plays a critical role in maintaining cellular homeostasis and responding to
various stress conditions by the degradation of intracellular components. In this narrative …