Effects and mechanisms of resveratrol on aging and age‐related diseases

DD Zhou, M Luo, SY Huang, A Saimaiti… - Oxidative medicine …, 2021 - Wiley Online Library
The aging of population has become an issue of great concern because of its rapid
increase. Aging is an important risk factor of many chronic diseases. Resveratrol could be …

Promising natural products in new drug design, development, and therapy for skin disorders: An overview of scientific evidence and understanding their mechanism of …

NA Mohd Zaid, M Sekar, SR Bonam… - Drug design …, 2023 - Taylor & Francis
The skin is the largest organ in the human body, composed of the epidermis and the dermis.
It provides protection and acts as a barrier against external menaces like allergens …

[HTML][HTML] Impact of oxidative stress on male and female germ cells: implications for fertility

RJ Aitken - Reproduction, 2020 - rep.bioscientifica.com
Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …

Health benefits of resveratrol administration

S Galiniak, D Aebisher… - Acta biochimica …, 2019 - abp.ptbioch.edu.pl
Resveratrol is a polyphenol that is abundant in grape skin and seeds. Food sources of
resveratrol include wine, berries, and peanuts. This compound has many properties …

[HTML][HTML] Interplay between oxidative stress, SIRT1, reproductive and metabolic functions

F Alam, H Syed, S Amjad, M Baig, TA Khan… - Current research in …, 2021 - Elsevier
Silent information Regulators (SIRT1) gene stimulates antioxidants' expression, repairs cells
damaged by oxidative stress (OS), and prevents the cells' dysfunction. In particular, the role …

Key signaling pathways in aging and potential interventions for healthy aging

M Yu, H Zhang, B Wang, Y Zhang, X Zheng, B Shao… - Cells, 2021 - mdpi.com
Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …

[HTML][HTML] Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina

N Wang, Z Luo, M Jin, W Sheng, HT Wang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
It is currently believed that aging is closely linked with mitochondrial dysfunction, and that
resveratrol exhibits anti-aging and neuroprotective effects by improving mitochondrial …

[HTML][HTML] Resveratrol prevents sarcopenic obesity by reversing mitochondrial dysfunction and oxidative stress via the PKA/LKB1/AMPK pathway

Y Huang, X Zhu, K Chen, H Lang, Y Zhang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: The concept of sarcopenic obesity refers to low muscle mass coupled with high
adiposity in older adults. Sarcopenic obesity is a new medical challenge that imposes …

Mechanisms of aging and potential role of selected polyphenols in extending healthspan

GL Russo, C Spagnuolo, M Russo, I Tedesco… - Biochemical …, 2020 - Elsevier
Aging became a priority in medicine due to the rapid increase of elderly population and age-
related diseases in the Western countries. Nine hallmarks have been identified based on …

Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development

BR Silva, JRV Silva - Animal reproduction science, 2023 - Elsevier
In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …