The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response
The complicated interactions between Leishmania and the host antigen-presenting cells
(APCs) have fundamental effects on the final outcome of the disease. Two major APCs …
(APCs) have fundamental effects on the final outcome of the disease. Two major APCs …
Leishmania exosomes and other virulence factors: Impact on innate immune response and macrophage functions
VD Atayde, K Hassani, A da Silva Lira Filho… - Cellular …, 2016 - Elsevier
Leishmania parasites are the causative agents of the leishmaniases, a collection of vector-
borne diseases that range from simple cutaneous to fatal visceral forms. Employing potent …
borne diseases that range from simple cutaneous to fatal visceral forms. Employing potent …
Mechanisms of immune evasion in leishmaniasis
G Gupta, S Oghumu, AR Satoskar - Advances in applied microbiology, 2013 - Elsevier
Diseases caused by Leishmania present a worldwide problem, and current therapeutic
approaches are unable to achieve a sterile cure. Leishmania is able to persist in host cells …
approaches are unable to achieve a sterile cure. Leishmania is able to persist in host cells …
Leptin functions in infectious diseases
Leptin, a pleiotropic protein has long been recognized to play an important role in the
regulation of energy homeostasis, metabolism, neuroendocrine function, and other …
regulation of energy homeostasis, metabolism, neuroendocrine function, and other …
Leishmania GP63 Alters Host Signaling Through Cleavage-Activated Protein Tyrosine Phosphatases
With more than 12 million people affected worldwide, 2 million new cases occurring per
year, and the rapid emergence of drug resistance and treatment failure, leishmaniasis is an …
year, and the rapid emergence of drug resistance and treatment failure, leishmaniasis is an …
Impact of Leishmania metalloprotease GP63 on macrophage signaling
The intramacrophage protozoan parasites of Leishmania genus have developed
sophisticated ways to subvert the innate immune response permitting their infection and …
sophisticated ways to subvert the innate immune response permitting their infection and …
[HTML][HTML] The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury
ZZ Chong, K Maiese - Histology and histopathology, 2007 - ncbi.nlm.nih.gov
Interest in the diverse biology of protein tyrosine phosphatases that are encoded by more
than 100 genes in the human genome continues to grow at an accelerated pace. In …
than 100 genes in the human genome continues to grow at an accelerated pace. In …
The pathogenicity and virulence of Leishmania-interplay of virulence factors with host defenses
Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …
genus Leishmania. Infection by different species of Leishmania results in various host …
Absence of Metalloprotease GP63 Alters the Protein Content of Leishmania Exosomes
Protozoan parasites of Leishmania genus are able to successfully infect their host
macrophage due to multiple virulence strategies that result in its deactivation. Recent …
macrophage due to multiple virulence strategies that result in its deactivation. Recent …
Leishmania-Induced Inactivation of the Macrophage Transcription Factor AP-1 Is Mediated by the Parasite Metalloprotease GP63
Leishmania parasites have evolved sophisticated mechanisms to subvert macrophage
immune responses by altering the host cell signal transduction machinery, including …
immune responses by altering the host cell signal transduction machinery, including …