Pancreatic neuroendocrine tumors (PanNENs) are rare sporadic cancers or develop as part
of hereditary syndromes. PanNENs can be both functioning and non-functioning based on …

Pancreatic neuroendocrine tumors (PNETs) are known to be the second most common
epithelial malignancy of the pancreas. PNETs can be listed among the slowest growing as …

Purpose: GEP-NENs are rare malignancies with increasing incidence. Their molecular
characteristics are still undefined. We explored the underlying biology of GEP-NENs and the …

Metabolic alterations within mitochondria, encompassing processes such as autophagy and
energy metabolism, play a pivotal role in facilitating the swift proliferation, invasion, and …

Gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs) are rare diseases
encompassing pancreatic (PanNETs) and ileal NETs (SINETs), characterized by …

Pancreatic adenocarcinoma is the seventh leading cause of cancer death in the world and
the most common type pf pancreatic cancer. Unfortunately, less than 20% of patients are …

Abstract AJCC TNM stage and WHO grade (G) are two widely used staging systems to guide
clinical management for pancreatic neuroendocrine neoplasms (panNENs), based on …

Refined risk stratification for gastroenteropancreatic neuroendocrine tumors (GEP‐NETs)
has the potential to improve comparisons of study populations across clinical trials and …

Background: The four major pathways in gastroenteropancreatic neuroendocrine
neoplasms (GEP-NENs) including chromatin remodeling, DNA damage repair, activation of …

Objective To investigate the effect of overexpression of the oncogenic transcription factor
ELF4 on proliferation and apoptosis in human insulinoma cells and explore the underlying …