Synchronization of molecular, metabolic, and cardiovascular circadian oscillations is
fundamental to human health. Sleep-disordered breathing, which disrupts such temporal …

Objective/Hypothesis The ADHERE Registry is a multicenter prospective observational
study following outcomes of upper airway stimulation (UAS) therapy in patients who have …

Rationale: Approximately one-third of patients with obstructive sleep apnea (OSA) treated
with hypoglossal nerve stimulation (HGNS) therapy are incomplete responders, despite …

Objective To perform a systematic review and meta-analysis for studies evaluating
hypoglossal nerve stimulation (HNS) clinical outcomes in the treatment of moderate to …

Elevated loop gain, consequent to hypersensitive ventilatory control, is a primary
nonanatomical cause of obstructive sleep apnoea (OSA) but it is not possible to quantify this …

Obstructive sleep apnea (OSA) is a common disorder associated with cardiovascular
disease (CVD). One theory to explain this relationship proposes that OSA can induce …

Importance Many adults with obstructive sleep apnea (OSA) use device treatments
inadequately and remain untreated. Objective To determine whether combined palatal and …

Upper airway stimulation (UAS) has been shown to reduce severity of obstructive sleep
apnoea. The aim of this study was to identify predictors of UAS therapy response in an …

Study objective To synthesize evidence from available studies on the relative efficacies of
continuous positive airway pressure (CPAP), mandibular advancement device (MAD) …

Introduction: Obstructive sleep apnea is an important and common disorder with associated
health risks. Assuring successful longitudinal management is vital to patient health and …