[HTML][HTML] Exhaled markers of pulmonary disease
SA Kharitonov, PJ Barnes - … journal of respiratory and critical care …, 2001 - atsjournals.org
There has recently been an explosion of interest in the analysis of breath constituents as a
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …
Exploring the monocrotaline animal model for the study of pulmonary arterial hypertension: A network approach
Pulmonary arterial hypertension (PAH) is responsible for the premature death mainly
because of progressive and severe heart failure. This disease is characterized by increased …
because of progressive and severe heart failure. This disease is characterized by increased …
Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice
YY Zhao, Y Liu, RV Stan, L Fan, Y Gu… - Proceedings of the …, 2002 - National Acad Sciences
Caveolins are important components of caveolae, which have been implicated in vesicular
trafficking and signal transduction. To investigate the in vivo significance of Caveolins in …
trafficking and signal transduction. To investigate the in vivo significance of Caveolins in …
Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
Background—Hypoxia-induced pulmonary hypertension is a major cause of morbidity and
mortality. Hypoxia induces pulmonary vasoconstriction, in part, by decreasing endothelial …
mortality. Hypoxia induces pulmonary vasoconstriction, in part, by decreasing endothelial …
Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats
K Abe, H Shimokawa, K Morikawa, T Uwatoku… - Circulation …, 2004 - Am Heart Assoc
Primary pulmonary hypertension is a fatal disease characterized by endothelial dysfunction,
hypercontraction and proliferation of vascular smooth muscle cells (VSMCs), and migration …
hypercontraction and proliferation of vascular smooth muscle cells (VSMCs), and migration …
Role of nitric oxide in the pathogenesis of chronic pulmonary hypertension
Chronic pulmonary hypertension is a serious complication of a number of chronic lung and
heart diseases. In addition to vasoconstriction, its pathogenesis includes injury to the …
heart diseases. In addition to vasoconstriction, its pathogenesis includes injury to the …
Clinical aspects of exhaled nitric oxide
SA Kharitonov, PJ Barnes - European Respiratory Journal, 2000 - Wiley Online Library
There has been intense research into the role nitric oxide (NO) plays in physiological and
pathological mechanisms and its clinical significance in respiratory medicine. Elevated …
pathological mechanisms and its clinical significance in respiratory medicine. Elevated …
Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs
H Li, T Wallerath, T Münzel, U Förstermann - Nitric Oxide, 2002 - Elsevier
In many types of cardiovascular pathophysiology such as hypercholesterolemia and
atherosclerosis, diabetes, cigarette smoking, or hypertension (with its sequelae stroke and …
atherosclerosis, diabetes, cigarette smoking, or hypertension (with its sequelae stroke and …
Adenovirus-mediated lung vascular endothelial growth factor overexpression protects against hypoxic pulmonary hypertension in rats
C Partovian, S Adnot, B Raffestin, V Louzier… - American journal of …, 2000 - atsjournals.org
Chronic hypoxic pulmonary hypertension (PH) is associated with vasoconstriction and
structural remodeling of pulmonary vessels including narrowing of the arterial lumen and …
structural remodeling of pulmonary vessels including narrowing of the arterial lumen and …
The structural basis of pulmonary hypertension in chronic lung disease: remodelling, rarefaction or angiogenesis?
N Hopkins, P McLoughlin - Journal of anatomy, 2002 - Wiley Online Library
Chronic lung disease in humans is frequently complicated by the development of secondary
pulmonary hypertension, which is associated with increased morbidity and mortality …
pulmonary hypertension, which is associated with increased morbidity and mortality …