Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy

AE Pegg - Cancer research, 1988 - AACR
The polyamine-biosynthetic pathway represents an inviting target for the development of
agents inhibiting carcinogenesis and tumor growth. Polyamines play an essential role in the …

Hepatocarcinogenesis in the rat: the effect of promoters and carcinogens in vivo and in vitro

MA Moore, T Kitagawa - International review of cytology, 1986 - Elsevier
Publisher Summary The investigation of nutritional and other environmentally derived
influences in animal experiments has established that vast arrays of compounds are …

Enzymes of glutathione metabolism as biochemical markers during hepatocarcinogenesis

S Hendrich, HC Pitot - Cancer and Metastasis Reviews, 1987 - Springer
Enzymes of glutathione metabolism, particularly gamma-glutamyltransferase (GGT) and
glutathione S-transferase (GST), play a role in multistage hepatocarcinogenesis. The …

Dose response in butylated hydroxyanisole induction of forestomach carcinogenesis in F344 rats

N Ito, S Fukushima, S Tamano, M Hirose… - Journal of the …, 1986 - academic.oup.com
Abstract Groups of 50 6-week-old male F344 rats were given a powdered diet containing 0,
0.125, 0.25, 0.5, 1, or 2% butylated hydroxyanisole [(BHA) CAS: 25013-16-5] for 104 weeks …

Palladium (II) salt and complexes of spermidine with a six-member chelate ring. Synthesis, characterization, and initial DNA-binding and antitumor studies

C Navarro-Ranninger, F Zamora, I López-Solera… - Journal of inorganic …, 1992 - Elsevier
By reaction of spermidine trihydrochloride with K 2 PdCl 4 and PdCl 2 at different pH's, we
have synthesized the [sperH 3] 2 [PdCl 4] 3 (I).[PdCl 2 (sperH)] 2 [PdCl 4](II), and [(PdCl 2) 3 …

[PDF][PDF] Метаболизм L-аргинина (обзор)

ВГ Граник - Химико-фармацевтический журнал, 2003 - chem.folium.ru
В настоящее время в литературе в качестве основr ной функции Lrаргинина наиболее
часто рассматриваr ется способность этой аминокислоты окисляться в живом …

Platinum (II) and (IV) spermidine complexes. Synthesis, characterization, and biological studies

C Navarro-Ranninger, PA Ochoa, JR Masaguer… - Journal of inorganic …, 1994 - Elsevier
By reaction of K 2 PtCl 4 with spermidine we have synthesized two tris-platinum covalent
compounds of formula (PtI 2) 3 (sper) 2 and (PtCl 2) 3 (sper) 2, one ionic compound of …

The dual role of antioxidants in the modification of chemical carcinogenesis

R Kahl - Journal of Environmental Science & Health Part C, 1986 - Taylor & Francis
Contents: I. Introduction, II. A role of vitamins C and E in the chemotherapy of cancer? III.
Antitumorigenic action of antioxidants: Data survey IV. Inhibition of nitrosation: A case for …

The significance of selected biochemical markers in the characterization of putative initiated cell populations in rodent liver

HC Pitot, HP Glauert, M Hanigan - Cancer letters, 1985 - Elsevier
Biochemical 'markers' of neoplastic cells have been the subject of numerous investigations
during the past several decades. Recently, studies from a number of laboratories have …

Metabolism of L-arginine (a review)

VG Granik - Pharmaceutical chemistry journal, 2003 - Springer
At present, oxidation of L-arginine with the formation of nitric oxide–one of the main
regulators of cell metabolism–is usually considered as the main function of this amino acid …