Head and neck cystic lesions: a cytology review of common and uncommon entities

S Vazquez Salas, K Pedro, A Balram, S Syed… - Acta cytologica, 2022 - karger.com
Background: Cystic lesions of the head and neck are a diagnostic challenge since they are
seen in the clinical presentation of a wide variety of conditions. Herein, common and …

Precision medicine in head and neck cancers: genomic and preclinical approaches

G Miserocchi, C Spadazzi, S Calpona… - Journal of Personalized …, 2022 - mdpi.com
Head and neck cancers (HNCs) represent the sixth most widespread malignancy worldwide.
Surgery, radiotherapy, chemotherapeutic and immunotherapeutic drugs represent the main …

Human papillomaviruses sensitize cells to DNA damage induced apoptosis by targeting the innate immune sensor cGAS

E Gusho, LA Laimins - PLoS pathogens, 2022 - journals.plos.org
The cyclic GMP-AMP synthase (cGAS) is a critical regulator of the innate immune response
acting as a sensor of double-strand DNAs from pathogens or damaged host DNA. Upon …

[HTML][HTML] Three-dimensional collagen-based scaffold model to study the microenvironment and drug-resistance mechanisms of oropharyngeal squamous cell …

G Miserocchi, C Cocchi, A De Vita… - Cancer Biology & …, 2021 - ncbi.nlm.nih.gov
Objective: Squamous cell carcinoma (SCC) represents the most common histotype of all
head and neck malignancies and includes oropharyngeal squamous cell carcinoma …

EZH2 regulates a SETDB1/ΔNp63α axis via RUNX3 to drive a cancer stem cell phenotype in squamous cell carcinoma

S Balinth, ML Fisher, Y Hwangbo, C Wu, C Ballon… - Oncogene, 2022 - nature.com
Enhancer of zeste homolog 2 (EZH2) and SET domain bifurcated 1 (SETDB1, also known as
ESET) are oncogenic methyltransferases implicated in a number of human cancers. These …

PI3K/AKT/mTOR signaling pathway in HPV-driven head and neck carcinogenesis: therapeutic implications

F Aguayo, F Perez-Dominguez, JC Osorio, C Oliva… - Biology, 2023 - mdpi.com
Simple Summary A subgroup of cancers that arises in the zone of the head and neck
(HNCs) are caused by some types of human papillomavirus (HPV), so called high-risk (HR) …

Molecular detection methods in HPV-related cancers

J Williams, M Kostiuk, VL Biron - Frontiers in Oncology, 2022 - frontiersin.org
Human papillomavirus (HPV) is responsible for most cervical cancers and some head and
neck cancers, including oropharyngeal squamous cell carcinoma and sinonasal carcinoma …

Human papillomavirus and survival of sinonasal squamous cell carcinoma patients: a systematic review and meta-analysis

A Sharma, AL Tang, V Takiar, TM Wise-Draper… - Cancers, 2021 - mdpi.com
Simple Summary Human papillomavirus (HPV) has been associated with multiple cancers
in the anogenital and upper aerodigestive tracts. In the head and neck region, HPV-positive …

The role of exosomes in epithelial–to-mesenchymal transition and cell functional properties in head and neck cancer

NS Mastronikolis, E Kyrodimos, D Spyropoulou… - Cancers, 2023 - mdpi.com
Simple Summary According to WHO 2018 estimates, cancer is the second leading cause of
mortality worldwide after cardiovascular disease, accounting for one in six fatalities. Mortality …

HPV-related diseases in male patients: An underestimated conundrum

A Garolla, A Graziani, G Grande, C Ortolani… - Journal of …, 2024 - Springer
Purpose Human papillomavirus (HPV) infection is the most common sexually transmitted
disease, in males and females worldwide. While the role of HPV in female diseases is well …