L-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity

NF Khedr, RH Werida - Life Sciences, 2022 - Elsevier
Background Trazadone is an antidepressant and may affect reproductive hormones and
spermatogenesis. l-carnitine is an amino acid that exhibits antioxidant actions. This study …

Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice

S Wang, Q Chen, Y Zhang, F Zheng, T Xue, X Ge… - Reproductive …, 2020 - Elsevier
Abstract Hydrogen sulfide (H 2 S), a gaseous intracellular signal transducer, participates in
multiple physiological and pathological conditions, including reproductive conditions, and …

Novel findings from arsenic‑lead combined exposure in mouse testicular TM4 Sertoli cells based on transcriptomics

X Zheng, C Guo, Z Lv, J Li, H Jiang, S Li, L Yu… - Science of The Total …, 2024 - Elsevier
Abstract Arsenic (As) and lead (Pb) exist widespread in daily life, and they are common
harmful substances in the environment. As and Pb pollute the environment more often in …

[HTML][HTML] Sertoli cell-conditioned medium can improve blood-testis-barrier function and spermatogenesis in azoospermia mice induced by scrotal hyperthermia: An …

F Aghajanpour, R Soltani, A Afshar… - International Journal …, 2024 - ncbi.nlm.nih.gov
Background An increase in the temperature of the testis is associated with damage to the
epithelium of seminiferous tubules and disruption of sperm production. Objective The current …

Diagnosis of male central hypogonadism during childhood

RP Grinspon, S Castro, FG Brunello… - Journal of the …, 2021 - academic.oup.com
The diagnosis of male central (or hypogonadotropic) hypogonadism, typically based on low
luteinizing hormone (LH) and testosterone levels, is challenging during childhood since both …

Severe acute respiratory syndrome coronavirus 2 and male reproduction: relationship, explanations, and clinical remedies

J Xu, L He, Y Zhang, Z Hu, Y Su, Y Fang… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-2019) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has been an ongoing pandemic and worldwide public health …

[HTML][HTML] An in vitro testicular organoid model for the study of testis morphogenesis, somatic cell maturation, endocrine function, and toxicological assessment of …

TC Cham, F Ibtisham, A Al-Dissi, A Honaramooz - Reproductive Toxicology, 2024 - Elsevier
Male reproductive capacity has fallen considerably in recent decades; in addition, the
incidence of testicular cancer has increased in many developed countries. The cause of this …

Loss of Cx43 in murine Sertoli cells leads to altered prepubertal Sertoli cell maturation and impairment of the mitosis-meiosis switch

E Hilbold, O Distl, M Hoedemaker, S Wilkening, R Behr… - Cells, 2020 - mdpi.com
Male factor infertility is a problem in today's society but many underlying causes are still
unknown. The generation of a conditional Sertoli cell (SC)-specific connexin 43 (Cx43) …

[HTML][HTML] Evaluation of diagnostic value of pelvic MRI in endometriosis in comparison with surgical findings: A cross-sectional study

RN Moghadam, F Tamizi, SKR Ratki… - International Journal …, 2024 - ncbi.nlm.nih.gov
Background Endometriosis is a multifocal gynecologic disorder during the fertility period in
women. Magnetic resonance imaging (MRI) is an important diagnostic modality for this …

Comparing the effects and mechanisms of exposure to polystyrene nanoplastics with different functional groups on the male reproductive system

X Gao, K Xu, W Du, S Wang, M Jiang, Y Wang… - Science of The Total …, 2024 - Elsevier
After aging in the environment, some nanoplastics will carry different charges and functional
groups, thereby altering their toxicological effects. To evaluate the potential impact of aging …