Nephrotic syndrome results in hyperlipidemia and profound alterations in lipid and
lipoprotein metabolism. Serum cholesterol, triglycerides, apolipoprotein B (apoB) …

Abstract Purpose of Review Type 2 diabetes mellitus is widespread throughout the world
and is a powerful risk factor for the development of atherosclerotic cardiovascular disease …

A major challenge in human genetics is to identify the molecular mechanisms of trait-
associated and disease-associated variants. To achieve this, quantitative trait locus (QTL) …

Normal HDL activity confers cardiovascular and overall protection by mediating reverse
cholesterol transport and through its potent anti-inflammatory, antioxidant, and …

High density lipoproteins (HDL) possess a number of physiological activities. The most
studied and, perhaps, better understood is the ability of HDL to promote excess cholesterol …

High-density lipoprotein (HDL) plays an important role in lipid metabolism and especially
contributes to the reverse cholesterol transport pathway. Over recent years it has become …

Dyslipidemia refers to the abnormality of lipid metabolism. The aberrant lipid profiles are
usually characterized by elevated plasma levels of low-density lipoprotein cholesterol (LDL …

Several isoforms of apolipoprotein J/clusterin (CLU) are encoded from a single gene located
on chromosome 8 in humans. These isoforms are ubiquitously expressed in the tissues, and …

L-4F, an apolipoprotein AI (apoA-I) mimetic peptide (also known as APL180), was
administered daily by either intravenous (IV) infusion for 7 days or by subcutaneous (SC) …

Although High Density Lipoprotein Cholesterol (HDL-C) levels are inversely proportional to
cardiovascular risk in many studies, recent pharmacological interventional studies with HDL …