Intracellular lifestyle of Chlamydia trachomatis and host–pathogen interactions
K Stelzner, N Vollmuth, T Rudel - Nature Reviews Microbiology, 2023 - nature.com
In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …
[HTML][HTML] Plasmid-mediated virulence in Chlamydia
BJ Turman, T Darville, CM O'Connell - Frontiers in Cellular and …, 2023 - frontiersin.org
Chlamydia trachomatis infection of ocular conjunctiva can lead to blindness, while infection
of the female genital tract can lead to chronic pelvic pain, ectopic pregnancy, and/or …
of the female genital tract can lead to chronic pelvic pain, ectopic pregnancy, and/or …
[HTML][HTML] Multipurpose prevention technologies: opportunities and challenges to ensure advancement of the most promising MPTs
B Young Holt, JA Turpin, J Romano - Frontiers in Reproductive …, 2021 - frontiersin.org
The HIV/sexually transmitted infection (STI) syndemics and the unmet need for modern
contraceptive methods continue to pose significant health risks for women worldwide (1) …
contraceptive methods continue to pose significant health risks for women worldwide (1) …
[PDF][PDF] Host cell death during infection with Chlamydia: a double-edged sword
BS Sixt - FEMS Microbiology Reviews, 2021 - academic.oup.com
The phylum Chlamydiae constitutes a group of obligate intracellular bacteria that infect a
remarkably diverse range of host species. Some representatives are significant pathogens …
remarkably diverse range of host species. Some representatives are significant pathogens …
Keeping the host alive–lessons from obligate intracellular bacterial pathogens
Mammals have evolved sophisticated host cell death signaling pathways as an important
immune mechanism to recognize and eliminate cell intruders before they establish their …
immune mechanism to recognize and eliminate cell intruders before they establish their …
[HTML][HTML] Pgp3 protein of Chlamydia trachomatis inhibits apoptosis via HO-1 upregulation mediated by PI3K/Akt activation
M Shu, J Bu, W Lei, L Chen, Z Zhou, C Lu, C Chen… - Microbial …, 2023 - Elsevier
As an obligate intracellular pathogen, Chlamydia trachomatis assumes various strategies to
inhibit host cells apoptosis, thereby providing a suitable intracellular environment to ensure …
inhibit host cells apoptosis, thereby providing a suitable intracellular environment to ensure …
LncRNA ZEB1-AS1/miR-1224-5p / MAP4K4 axis regulates mitochondria-mediated HeLa cell apoptosis in persistent Chlamydia trachomatis infection
F Luo, Y Wen, L Zhao, S Su, W Lei, L Chen, C Chen… - Virulence, 2022 - Taylor & Francis
Persistent infection of Chlamydia trachomatis is thought to be responsible for the debilitating
sequelae of blinding trachoma and infertility. Inhibition of host cell apoptosis is a persistent …
sequelae of blinding trachoma and infertility. Inhibition of host cell apoptosis is a persistent …
Chlamydia trachomatis Pgp3 protein regulates oxidative stress via activation of the Nrf2/NQO1 signal pathway
M Shu, W Lei, S Su, Y Wen, F Luo, L Zhao, L Chen… - Life Sciences, 2021 - Elsevier
Aim Chlamydia trachomatis has evolved various strategies to alleviate oxidative stress of
host cells to maintain their intracellular survival. However, the exact mechanism of anti …
host cells to maintain their intracellular survival. However, the exact mechanism of anti …
[HTML][HTML] Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway
Y Wen, H Chen, F Luo, L Zhao, M Shu, S Su… - Frontiers in …, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …
Chlamydia trachomatis induces lncRNA MIAT upregulation to regulate mitochondria‐mediated host cell apoptosis and chlamydial development
F Luo, Y Wen, L Zhao, S Su, Y Zhao… - Journal of cellular and …, 2022 - Wiley Online Library
Chlamydia trachomatis persistent infection is the leading cause of male prostatitis and
female genital tract diseases. Inhibition of host cell apoptosis is the key to maintaining …
female genital tract diseases. Inhibition of host cell apoptosis is the key to maintaining …